Medical Director, Clinical Development Rare Cardiology

This is what you will do:

The Medical Director, Clinical Development, may lead or support the clinical subteam and the global program team to construct global clinical development plans and contribute to the development of asset level and therapeutic area strategies.

You will be responsible for:

• The design and execution of multiple clinical studies or clinical programs

• Represent Clinical Development on the Global Program Team (GPT) and in presentations at management and review committees (e.g., Clinical Document Review Committee, Development and Commercial Steering Committee)!

• May have up to 12 Medical Directors for the program studies and/or Clinical Development Scientists or provide medical oversight.

• Work with one or more clinical study teams in the preparation of clinical study related documents including protocols, charters, statistical summary reports, meeting presentations, publications, and clinical sections of regulatory documents

• Select appropriate advisory board participants and guide the team in preparation for meetings

• Critically evaluate available information about diseases of interest to the therapeutic area and the competitive landscape and synthesize information succinctly to support dissemination and incorporation into clinical development programs, asset plans and therapeutic area strategy

You will need to have:

• MD or equivalent

• 3+ years of clinical experience preferably within industry

• Experience as a medical monitor for clinical trials

• Publication in peer reviewed journals

• The duties of this role are generally conducted in an office environment. As is typical of an office based role, employees must, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; problem resolution; engage in nonlinear thought, analysis, and dialogue; collaborate; maintain general availability during standard business hours

We would prefer for you to have:

• Board Certification

• Knowledge of the assigned therapy area with the capability to interpret, discuss and represent trial or program level data.

• 5+ years of industry experience in clinical development

• Experience for medical responsibilities on a cross-functional team

• Basic statistical knowledge

• Understanding of general (and specific) therapeutic principles

• Experience designing industry sponsored clinical trials

• Broad experience in the principles of clinical trial methodology, statistics, data analysis and interpretation

• Experience authoring study essential documents, Clinical Study Reports, and regulatory documents

The Senior Medical Director Clinical Development will lead the clinical team for a high-visibility program and report to the Global Clinical Head. This is an excellent opportunity for an experienced and motivated drug developer to advance an innovative, late-stage study. 

The SD will provide medical leadership across late stage. Acting as a key medical expert on the study team(s), the SD may also serve as medical monitor as needed. 

In this role, the SD will work cross-functionally and mentor Physicians, Clinical Directors, and Clinical Development Scientists. The position may include direct and indirect managerial responsibilities for team members across the Clinical Development organization. The SD will also contribute to the development of regulatory, therapeutic area, and functional strategies. 

This position offers the opportunity to collaborate closely with enterprise-level, cross-functional teams, including AstraZeneca Business Units, CVRM, and strategic development partners. The ideal candidate will thrive in a fast-paced, proactive, and collaborative culture—demonstrating strong communication skills, scientific leadership, and the ability to drive impact across both internal and external teams. 

You will be responsible for:  

• Lead cross-functional clinical program teams to deliver high-quality studies and research strategies, ensuring scientific rigor and optimal benefit–risk management. 

• Serve as the clinical authority for assigned programs, overseeing study design, execution, data interpretation, and regulatory deliverables in compliance with GCP. 

• Provide strategic medical and scientific input across R&D, translational science, commercial, and business development activities, including due diligence and collaborations. 

• Mentor and develop Medical Directors, Clinical Development Scientists, and fellows to build organizational scientif