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Senior Technical Program Manager, Product Security

Chan Zuckerberg Initiative
Redwood City, United StatesRemotefull_timeVerifiedPosted 12 Feb 2026
💰 $261,800/yr($190,000/yr$261,800/yr)

About the role

The Chan Zuckerberg Initiative was founded in 2015 by Priscilla Chan and Mark Zuckerberg to help solve some of society’s toughest challenges — from curing or preventing disease to improving education and addressing the needs of our local communities. We provide the operational support across our areas of work.

The Team

Across our work in Science, Education, and within our communities, we pair technology with grantmaking, impact investing, and collaboration to help accelerate the pace of progress toward our mission. Our Operations organization provides the support needed to push this work forward. 

Operations consists of our Brand & Communications, Central Tech, Finance, People, Real Estate/Workplace/Events/Facilities/Security (REWFS), Strategy & Operations, and Ventures teams. These teams provide the essential operations, services, and strategies needed to support CZI’s progress toward achieving its mission to build a better future for everyone.

The Opportunity

We are seeking a Technical Program Manager with expertise in Application Security, specifically in identifying vulnerabilities and then scoping and implementing novel solutions to eliminate those weaknesses at scale. We don't just identify and fix security vulnerabilities - we go beyond by creating paved roads and secure frameworks to avoid security vulnerabilities in the first place. You will be expected to operate using in-depth subject-matter knowledge at a technical level with developers and engineers across large organizations. Your security and development experience will be relied upon to provide secure foundations to the application and infrastructure teams that underpin the CZI Enterprise.

The role will help shape the product and application security that protects scientific and educational innovation at the Chan Zuckerberg Initiative, Biohub and Learning Commons. You’ll work alongside a dynamic team of engineers, Product Managers, and Security Professionals, building shared tools and platforms that support a diverse group of Research Scientists, Data Scientists, AI Researchers, and Engineers tackling some of the world’s most complex problems. As part of the Information Security team, your work will directly impact all of CZI’s initiatives by ensuring the security and scalability of the technology solutions that drive our mission forward.

What You'll Do

  • Conceive, design, develop, and improve industry-leading security tooling, automation, architecture, and/or frameworks that enable enterprise teams at scale to deliver applications and services with appropriate security controls to meet evolving requirements for security and privacy
  • Identify and eliminate classes of security problems by shifting detection and prevention left into the development workflow
  • Provide just-in-time, actionable, technical security guidance to enterprise application and service teams
  • Ensure prioritization, resourcing, and timely delivery of work within a changing business environment
  • Collaborate with cross-functional teams to ensure security work is being prioritized and addressed
  • Drive end-to-end execution of technical security projects, including requirements gathering, scoping, status updates, and delivery milestones.
  • Establish and report metrics to track compliance, program health, and ongoing risk posture.
  • Coordinate with third-party vendors and auditors to augment internal security capabilities
  • Serve as a subject matter expert on infrastructure, architecture, and application security, offering guidance to technical and non-technical stakeholders.
  • Support security reviews, threat modeling, and incident response efforts for applications and production infrastructure.

What You'll Bring

  • 5+ years of technical program management or equivalent experience, with a specific focus on security or application security.
  • Demonstrated proficiency with secure SDLC processes and best practices for integrating security throughout the software development lifecycle.
  • Hands-on experience designing and managing security controls within CI/CD pipelines, using automation frameworks to enable secure code delivery and rapid remediation.
  • Familiarity with threat modeling, static and dynamic application security testing (SAST/DAST), and software composition analysis (SCA) tools.
  • Deep understanding of DevSecOps principles, security automation, and infrastructure-as-code security.
  • Experience driving the adoption of vulnerability management, architectural best practices, and incident response for cloud-native and distributed applications.
  • Knowledge of container security (Docker, Kubernetes), microservices architectures, and cloud platform security (AWS, Azure, GCP).
  • Experience leading end-to-end se

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Company

Chan Zuckerberg Initiative

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