Administrative Director, Clinical Trial Center for Neurotherapeutics

Site: The General Hospital Corporation

 

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

 

 

Job Summary

The Mass General Brigham Neuroscience Institute (NSI) seeks an accomplished Administrative Director to lead the operational and administrative infrastructure of the NSI Clinical Trial Center for Neurotherapeutics (CTC). This full-time leadership role is responsible for overseeing all aspects of clinical trial operations across a diverse and rapidly expanding portfolio, including regulatory operations, site management, multi-site coordination, compliance frameworks, industry partnerships, and performance oversight.

This role requires a highly experienced leader with deep expertise in multisite clinical trial project management and regulatory science, and a comprehensive understanding of the full clinical trial lifecycle from protocol design and startup through conduct, monitoring, and closeout. The administrative director will play a critical role in building and implementing the vision, structure, and infrastructure of the CTC, ensuring effective and streamlined coordination between the central coordinating center and all participating sites.

The Administrative Director will partner closely with the Director of the Clinical Trial Center and will report to the Senior Research Administrator for the NSI. This is a strategic, hands-on leadership role that calls for strong management skills, collaboration across teams, and the ability to work effectively with MGB Clinical Trial office leadership, investigators, industry sponsors, regulatory partners, and internal groups such as biostatistics, finance, and clinical operations teams.

The CTC portfolio includes coordination of adult and pediatric studies, inpatient and outpatient trials, innovative gene and cell-based therapeutics and biorepositories. The Administrative Director will ensure operational excellence, regulatory rigor, and high quality execution across all program areas.

 

Qualifications

Principal Duties and Responsibilities

• Provide strategic and operational leadership for the day-to-day management of the Clinical Trial Center.
• Oversee regulatory and compliance operations, ensuring adherence to federal, state, institutional, and sponsor requirements.
• Direct staffing strategy including workforce planning, recruitment, onboarding, training, performance management and retention of a high-performing, multidisciplinary team.
• Provide direct supervision to multiple direct reports and foster a culture of accountability, collaboration, and continuous improvement.
• Lead quality oversight initiatives and implement process improvements to enhance efficiency, accuracy, and audit/regulatory readiness across all trials.
• Drive business development efforts and serve as a key liaison for pharmaceutical, biotechnology, and device company partnerships
• Provide support for teams conducting clinical research and resources to track performance and ensure efficiency.  
• Partner with the Center Director and the NSI Director of Finance on financial planning, budgeting, forecasting, and allocation of operational resources to support sustainable growth.
• Partner with the NSI Executive Director, Clinical Trial Center Director and MGB development team on philanthropy proposals and reporting.
• Promote a high-performing culture grounded in collaboration, innovation, regulatory excellence, and patient-centered research excellence.

Fiscal Responsibility

• Provides strategic financial leadership for clinical trial programs, including budgeting, financial planning, and oversight of sponsor-funded and grant-supported activities. Oversees direct program resources, including staffing, overtime, and operational expenses. Maintains sensitive fiscal information and ensures appropriate internal controls are in place. 

Supervisory Responsibility

• Direct reports are anticipated as the function grows, this role will play a key part in building and leading the team. Provides broad oversight of site clinical research administrative operations, serving as a leader, subject matter expert, and resource to staff across clinical trials units. 

Qualifications

• Bachelor’s degree in related field required;