Senior Scientist-Analytical

Use Your Power for Purpose

As a Senior Scientist in Analytical Chemistry at Pfizer CentreOne, you will lead and execute complex analytical method development, validation, and troubleshooting activities to support sterile injectable product development and technical transfers. You will be a key contributor to the success of Pfizer’s external partnerships and internal programs, ensuring analytical excellence and regulatory compliance throughout the product lifecycle.

What You Will Achieve

In this role, you will:

• Design, develop, and validate analytical methods for small molecules and biologics, including HPLC, LC-MS, and compendial methods.

• Provide technical leadership in analytical strategy for method development, validation, and method transfers.

• Interpret and integrate analytical data to support regulatory submissions, investigations, and product characterization.

• Collaborate cross-functionally with formulation scientists, microbiologists, and process engineers to ensure seamless technical transfer and product development.

• Maintain and improve laboratory instrumentation and systems in compliance with GLP, cGMP, and Pfizer Quality Standards.

• Document experimental work with precision and clarity to ensure reproducibility and audit readiness.

• Participate in project meetings, presenting data and providing scientific insights to guide decision-making.

• Contribute to and influence goals at the work group/project team level, providing mentoring and training within the team.

• Manage time effectively and develop short-term work plans to ensure project milestones are met.

• Apply technical skills and knowledge proactively in projects, developing scientific activities to support team goals.

• Make decisions to resolve moderately complex problems, receiving instructions on more complex issues.

• Work under limited supervision with periodic review, ensuring compliance with Good Manufacturing Practice (GMP) and Good Laboratory Practices (GLP).

• Prepare, review, and verify technical documents, including validation protocols, analytical test procedures, investigation reports, and change controls.

• Develop analytical methodologies and strategies to progress biotherapeutic products, managing the development, qualification, validation, and transfer of assays.

• Work directly with external parties, such as 3rd party analytical labs and Contract Manufacturing Organizations, and collaborate with other Pfizer divisions.

• Assemble multi-disciplined teams to assess and solve problems, providing technical expertise and support to the analytical staff.

Here Is What You Need (Minimum Requirements)

• Applicant must have BA/BS with at least 4 years of experience; OR MBA/MS with at least 2 years of experience; OR PhD/JD with any years of experience; OR an Associates degree with 8 years of experience; OR HS diploma with 10 years of experience.

• Demonstrated technical skills and scientific expertise in analytical method development and troubleshooting

• Proven proficiency with both analytical laboratory data and process-relevant data

• Working in a regulated environment, such as Good Laboratory Practices (part of GxP)

• Strong written and verbal communication skills

• Proficiency in MS Office

• Ability to manage multiple projects and prioritize tasks effectively

• Customer facing experience

• Proficiency in analytical techniques, particularly LC-MS, HPLC

Bonus Points If You Have (Preferred Requirements)

• Relevant experience in the pharmaceutical industry

• Solid understanding of separation technologies such as liquid chromatography, analytical ultracentrifugation, and field flow fractionation

• Strong problem-solving skills and the ability to make decisions to resolve moderately complex problems

• Experience in mentoring and guiding team members

• Ability to work collaboratively in a team environment

• Strong attention to detail and accuracy

PHYSICAL/MENTAL REQUIREMENTS

Laboratory Presence

Frequent work in analytical, microbiological, and bioassay laboratories is required. This includes handling chemicals and cytotoxic/highly potent compounds (OEB-5 classification) with appropriate engineering controls and PPE.

Mobility and Dexterity

Occasional light lifting and extended periods of sitting or standing are expected. The role may involve bending, reaching, and working with lab instrumentation and data systems.

Cognitive Demands<