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Job Description

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as a Research Associate Scientist TME Tumor Assays, ODDU where you will be a highly motivated and talented Molecular Biologist and contribute to the Tumor Microenvironment (TME) Disruptor. You will also make contributions from the lab to advance novel and differentiated therapeutic modalities towards preclinical and clinical milestones. As part of the Oncology Drug Discovery Unit (ODDU), you will report to Associate Director, reporting into the Tumor Biology Lab Head within the group.

How you will contribute:

• Independently plans new experimental approaches to specific problems/scientific projects using scientific theory and technical literature with flexibility to troubleshoot and change experimental design when necessary.

• Utilize technical literature to implement novel procedures, changes and improvements within a project. Can duplicate and modify experimental procedures based on the literature.

• Interpret results of complex experiments and documents results according to company policies in electronic lab notebook.

• Prepare and present comprehensive technical or project reports and formal presentations to a range of internal audiences.

• Work with cultured cell lines and primary cells from multiple species (murine, human) using sterile technique to perform assay development, model characterization, and screening.

• Hands-on experience with basic molecular biology tools, including western blotting, qRT-PCR/digital PCR, molecular cloning and lenti-virus package and infection.

• Familiarity with CRISPR/Cas9 technology and experience using genetic tools for tumor cell/primary cell gene manipulation.

Minimum Requirements/Qualifications:

• MS in a scientific discipline with 3+ years' experience, or BS with 5+ years' experience

• Industry experience is preferred, but not required.

• Hands-on experience in western blotting, qRT-PCR/digital PCR, molecular cloning and CRISPR/Cas9 mediated gene manipulation is required.

• Ability to work independently under minimal supervision in carrying out data acquisition, analysis, storage and reporting.

• Ability to work in BSL2 laboratory handling cancer cell lines and functional lymphocytes.

• Experience with cytometers and data analysis software, such as FlowJo and GraphPad Prism is preferred.

• Proficiency with common software for documentation and presentation of results at different levels of granularity and documentation in electronic lab notebook.

• Excellent analytical, organizational, interpersonal and time management skills

• Strong team player who thrives in a dynamic, 'biotech-like' environment.

• Takeda's high-engagement and ONE Research DEI culture is an important factor in our success; we seek team members who will contribute to and further strengthen that culture in all ways of working.

• Right attitude (agile, curious, positive, open-minded, "can-do" mindset), must be willing and able to be "hands on," results-oriented mindset.

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow