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General Supervisor, Oncology

BillionToOne
Menlo Park, USAfull_timePosted 17 Jun 2026

About the role

<div class="content-intro"><h2><strong>A Rare Opportunity to Shape the Future of Genomics</strong></h2> <p>Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.</p> <p>Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.</p> <p>If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.</p></div><p data-start="844" data-end="1222">BillionToOne is seeking a <strong>Clinical Laboratory General Supervisor (GS) </strong>to support our Oncology product, Northstar, in a high-complexity CLIA laboratory environment. This role provides general supervision of personnel and daily laboratory operations, ensuring regulatory compliance, quality, and operational excellence across end-to-end cancer blood sample processing.</p> <p data-start="1224" data-end="1592">This is a hands-on leadership role in a fast-growing, high-throughput molecular diagnostics lab. The General Supervisor will serve as a key operational leader and first point of escalation for CLS and CLA, partnering closely with the&nbsp;Technical Supervisor, Laboratory Director, and Quality team.</p> <p data-start="1594" data-end="1771">This is an onsite position supporting the Monday–Friday Mid Shift (11:30 AM – 8:00 PM), with a planned transition to a PM shift (3:00 PM – 11:30 PM) later this year.</p> <p><strong>Responsibilities:</strong></p> <ul> <li><strong>General Supervision &amp; Leadership</strong> <ul> <li>Serve as a&nbsp;designated CLIA General Supervisor for high-complexity testing in accordance with 42 CFR Part 493 and CAP accreditation standards</li> <li>Provide&nbsp;day-to-day supervision of laboratory personnel, including CLSs and CLAs, during the pre-analytic, analytic, and post-analytic phases of testing</li> <li>Act as the&nbsp;primary escalation point for technical, operational, and personnel issues during assigned shifts</li> <li>Oversee staffing, scheduling, shift handoffs, and workloa

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BillionToOne

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