This is for a newly created role in GSK’s new oligo biology group. We are building a team of scientists to lay the groundwork necessary to support GSK’s internal oligo screening platform.  This involves securing the appropriate equipment/instrumentation, planning and conducting experiments, and staying up to date on the latest technology in the field. The primary purpose will be to manage screening efforts across a range of diseases and targets, with the potential to serve as the oligo lead for a disease program. A range of oligo types will be explored, including siRNA, splice-switching oligos (SSOs), antisense oligos (ASOs) and RNA editors.

Key Responsibilities

This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following…

• Be able to plan and conduct high throughput oligo screens (96 well and 384 well) aided by automated liquid handlers for GSK oligo portfolio
• Optimize conditions and maintain various cell lines, and work with primary cells (liver, lung, CNS), as well as iPSC-derived cell models
• Establish and Run protein analysis experiments using Western blots and ELISAs
• Isolate and handle RNA for use in downstream assays such as qPCR and sequencing
• Build and maintain relationships with other team leads
• Organize, analyze, and present data across teams
• Help establish workflows and SOPs for developing team
• Potential to serve as oligo lead on project teams

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• Masters with 5+ years of experience in Biology, biotechnology and related fields
• Experience working in a biopharma environment and have a record of past success.
• Experience with cell culture, RNA and protein handling skills, high throughput 96/384 well screening.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Ph.D with 3+ years’ experience in Molecular biology

• A working knowledge of data analytics is a plus
• Familiarity with ddPCR is a plus
• Experience with automated liquid handlers is a plus
• Familiarity with cell imaging, FACS analysis, RNA sequencing technologies, management experience

#LI-GSK

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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