Advisor - Biophysical Chemist

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$133,500 - $217,800

We are seeking a highly skilled and motivated Biophysical Chemist to join our research team.  This position lies at the interface of the Protein Biosciences and Computational Science groups at the Lilly Biotechnology Center in San Diego, where the successful candidate will be part of a team responsible for building capabilities to take full advantage of Artificial intelligence and Machine Learning (AI/ML)–based design of new therapeutic modalities. The primary responsibilities of this role will be to implement a variety of tools to characterize biophysical properties of potential therapeutics, and to develop new approaches for high-throughput characterization to support machine learning and AI-based molecule design efforts. 

Primary Responsibilities:

• Designing and implementing experiments for the biophysical characterization of protein-based therapeutics.

• Translating biophysical characterization approaches into high-throughput characterization to support ML data needs and AI design strategies

• Embrace and celebrate diversity by using a relevant and unique background and set of experiences to provide new ideas to deliver innovative solutions drugging novel targets.

• Strong communication (oral and written), organizational, and leadership skills are expected.

Basic Qualifications

• Ph.D. in biophysical chemistry, biochemistry, protein chemistry, or related field OR an MS in related field and 7+ years of relevant industrial experience.

• Strong core proficiency in protein biophysical chemistry, with a focus on the characterization of proteins using a variety of approaches; including tools that assess stability, conformation, and association state.

• Strong publication record

Additional Skills and Preferences

• Familiarity with related structural biology tools and computational assessment of proteins based on structure.

• Prior experience in the characterization of antibody and antibody-like molecules

• Prior experience in machine-learning applications

• Exceptional problem solving and critical thinking skills.

• Ability to work productively and collaboratively in an interdisciplinary team environment.

• Ability to prioritize multiple activities and thrive in a setting that requires quick movement between scientific challenges and comfort with ambiguity.

• An active scientific curiosity and interest for complementary disciplines within the pharmaceutical industry.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

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