Senior Scientist, Analytical Development and Quality Control (Drug Product)

<p><strong><em>&nbsp;</em></strong><strong><em>Company</em></strong></p> <p><em>Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.</em></p> <p><em>&nbsp;</em><strong><u>Position</u></strong></p> <p>Nurix Therapeutics seeks an experienced Senior Scientist to join the Analytical Development and Quality Control group. The Senior Scientist will be responsible for drug product (DP) analytical development, including method development, oversight of method validation at CDMOs, and lifecycle management in support of Nurix’s oncology and inflammation &amp; immunology (I&amp;I) programs.</p> <p>This position provides technical oversight of analytical method development, validation, and testing conducted at external CDMO/CRO partners. The Senior Scientist will author analytical development reports and IND/IMPD/NDA sections and support late-phase tech transfer and validation activities. This role will also contribute to analytical development for new drug products and dosage forms. The Senior Scientist will work closely in cross-functional teams to ensure alignment and integration of analytical and QC strategies across development stages.</p> <p>The ideal candidate will have expertise in chromatographic and dissolution method development, stability studies, and phase-appropriate validation and control strategies, along with demonstrated experience supporting late-phase development and regulatory submissions.</p> <p>This position is onsite at Nurix headquarters in Brisbane, CA.</p> <p><strong>Key responsibilities include:</strong></p> <ul> <li>Lead analytical method development validation and lifecycle management for drug product formulations, including amorphous solid dispersions (ASDs) and lipid-based systems</li> <li>Support PPQ activities, commercialization, commercial QC, and lifecycle management for drug product analytical methods and control strategies</li> <li>Design and oversee DP development, registration batch, and commercial stability programs, including protocol development and trend analysis</li> <li>Author an