Sr. Scientist, Analytical R&D

Job Description

Senior Scientist (Protein & Enzyme Analytics) – Data Rich Measurements

Job Description:

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology, we collaborate to discover the next medical breakthrough.

As a Senior Scientist in Analytical Enabling Capabilities, you will work with a highly collaborative team to advance the development pipeline. You will be primarily responsible for developing analytical methods for complex small molecules, peptides, oligonucleotides, protein-based therapeutics, and emerging modalities in our portfolio. You will work side by side with process chemists to deploy innovative technologies and analytical workflows for high-throughput analysis and characterization across fast-paced laboratory settings (Method Discovery, Protein Engineering, Biocatalysis). As a member of our team, you will be joining a diverse group of scientific problem solvers, who are dedicated to creating the life-changing products of tomorrow.

Education Minimum Requirement:

• PhD in Chemistry or a related field OR

• Masters in Chemistry or related field with 5+ years of experience OR

• Bachelors in Chemistry or related field with 8+ years of experience

Required Experience and Skills:

• 3+ years of thorough understanding of chromatography and mass spectrometry within method development.

• Creative problem solving in scientific research

• Excellent written and verbal communication

• Strong track-record of innovation translated into high impact factor publication

• Bioanalytical techniques, separations and python coding

• LC/MS analysis of proteins/enzymes, HDX-MS and high-throughput analysis

• Enzyme kinetics

Preferred Experience and Skills:

• Expertise in method development and troubleshooting of high-throughput fast chromatographic methods including reversed phase, ion exchange, size exclusion chromatography, etc.

• Hands-on experience in protein characterization techniques such as intact mass analysis, native-MS, peptide mapping analysis for the identification of PTMs, HCPs and disulfide mapping

• Strong understanding of designing and executing enzyme kinetics and functional activity assays

• Willing to learn new technologies and automation

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

AR&D

Required Skills:

Accountability, Accountability, Adaptability, Analytical Method Development, Anion Exchange Chromatography, Assay Development, Bioanalytical Analysis, Biochemical Assays, Cell-Based Assays, Chromatographic Techniques, Column Chromatography, Communication, Enzyme Kinetics, Gas Chromatography-Mass Spectrometry (GC-MS), GMP Environments, Healthcare Innovation, Innovative Thinking, Liquid Chromatography-Mass Spectrometry (LC-MS), Mass Spectrometry (MS), Nuclear Magnetic Resonance (NMR) Analysis, Process Analytical Technology (PAT), Protein Engineering, Proteomics, Scientific Research, Spectrometry {+ 4 more}

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteri