Jobs and Careers
HE

Manager, Strategy & Business Operations

Helix
San Mateo, United StatesRemotefull_timeVerifiedPosted 22 Dec 2025
💰 $148,000/yr($109,000/yr$148,000/yr)

About the role

Who We Are & What We Do At Helix, our mission is simple: to help everyone improve their lives through their DNA.
Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics. 
What is special about this role:The Strategy & Business Operations team is the swiss-army knife of Helix. We help define, scope, and operationalize critical initiatives across the business. As part of a small team that works closely with the leadership team, you will be at the center of the inner workings of how a company makes both strategic and operational decisions to help bring a shared vision to life. You will get your hands dirty across multiple functional areas – from Business Development and Finance, to Product and Science, and more. This is a great opportunity for a self-starter with a strong foundation in healthcare, is energized by the unknown, and thrives in a fast-paced environment.
As a Manager, Strategy & Business Operations you will:
  • Work closely with the leadership team to identify, develop, and implement high-priority, strategic initiatives
  • Provide strategic insight to complex, cross-functional efforts to ensure alignment with business priorities
  • Leverage data and business insights to pinpoint operational needs and recommend process improvements
  • Spearhead the development and execution against detailed project plans to support successful launches
  • Conduct market research to validate hypotheses and identify opportunities to accelerate growth
  • Support the evaluation of strategic opportunities (e.g. partnerships, acquisitions, etc.)
  • Contribute to the development of Board meeting materials and investor presentations
  • Act as a key resource in resolving critical and time-sensitive challenges facing the business

About you:
  • BA or BS degree
  • 4–6 years of experience in consulting, business operations, corporate strategy, or similar role at a high-growth startup; experience in health tech industry preferred
  • Proven track record of delivering results, even when outside past expertise
  • Strategic, structured problem-solver who can break down ambiguous asks into concrete plans
  • Ability to operate autonomously and influence stakeholders at all levels
  • Capable of owning the details, while still keeping the big picture in mind
  • Adaptable to shifting priorities, but can bring stability to a dynamic environment
  • Excellent interpersonal and communication skills, both written and verbal
  • Ability to tell a story focused on insights and data, not just a summary of data alone
  • Have a knack for learning new things fast
  • Highly proficient with G Suite (Sheets, Docs, Slides), macOS

Pluses:
  • Experience with Tableau, Thoughtspot, Hubspot
  • Experience working with health systems or payers

Expected Interview Process:1) Recruiter Screen 2) Manager Screen 3) Virtual Onsite 4) Offer 
Expected Pay For This Role:There are 3 distinct parts to your Helix offer: 1) Base Salary 2) Annual Bonus 3) Equity 
  • Expected Helix Base: $109,000 - $148,000
  • Expected Helix Discretionary Annual Bonus: 10% of your annual salary
  • Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.

Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:
  • Comprehensive Health Insurance with Date of Hire eligibility 
    • Above average employer paid premium coverage 
  • 12 weeks Helix Paid Parental Leave option 
  • 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
  • Comprehensive Well-Being Benefits 
  • Flexible PTO
  • Home office stipend 

What To Expect During Your First 90 days:
  • First 30 days: you’ll spend time learning the Helix way, completing training and onboarding for your roles, and getting introduced to your team and relevant stakeholders. You’ll also gain a deeper understanding of our customers, our products, the i

Apply for this role

Generate a tailored application kit with a matched cover letter, interview prep, and CV highlights — in under 60 seconds.

Apply Now →Generate Application Kit

Free account required — sign up in 30s

Company

Helix

View company profile →