Clinical Trial Liaison / Clinical Research Lead

Clinical Research Lead (Site Liaison) - Eastern or Central time zone

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development

We are currently seeking a Clinical Trial Enrollment Liaison to join our diverse and dynamic team. As a Clinical Trial Enrollment Liaison at ICON, you will play a pivotal role in designing and analyzing clinical trials, interpreting complex medical data, and contributing to the advancement of innovative treatments and therapies.

What you will be doing

Primary Responsibilities: This job description is intended to provide a general overview of the job requirements at the time it was prepared. The job requirements of any position may change over time and may include additional responsibilities not specifically described in the job description. Consult with your supervision regarding your actual job responsibilities and any related duties that may be required for the position.

Clinical Investigator Management

• Accountable for the full spectrum of investigator engagement from identification and qualification through enrollment, and support database lock, and study closeout

• Serve as a clinical trial scientific ambassador, ensuring investigators deeply understand protocol intent, scientific rationale, and patient eligibility requirements

• Develop and sustain strategic, high-trust relationships with investigators that span trials and therapeutic areas

• Influence enrollment by co-creating tailored recruitment strategies aligned with site capabilities, patient population realities, and study objectives

• Proactively find opportunities to reach new patients, accelerate enrollment and increase impact at priority sites, including for example, novel site models, community-based research initiatives etc

• Capture and elevate critical insights from sites to optimize feasibility, protocol design, and study conduct

Clinical Trial Management

• Lead site-level strategy and risk planning to ensure strong and predictable enrollment and data delivery

• Leverage performance metrics to anticipate issues, intervene decisively, and maintain momentum toward clinical milestones

• Drive inspection readiness as a continuous discipline across sites

• Collaborate across functions and with vendor partners to resolve operational barriers, ensuring delivery with speed and quality

• Maintain advanced understanding of local treatment paradigms and standard of care to influence strategic country/site selection and protocol localization

• Provide oversight and quality assurance for vendor monitoring, escalating risks proactively

• Where applicable, lead end-to-end management of Post-Marketing Safety Studies in compliance with local regulations

Business Management and Engagement

• Cultivate a portfolio of strategically aligned, high-impact investigators who consistently prioritize sponsor trials

• Enable an exceptional investigator experience by being a responsive, knowledgeable, and valued scientific partner

• Collaborate cross-functionally (e.g., Medical, Clinical, Study Delivery) to align on trial and site priorities, troubleshooting challenges with urgency and creativity

• Conduct data-informed site prospecting and prioritization, contributing to trial competitiveness and regional strategic execution

• Maintain scientific fluency and therapeutic expertise to lead meaningful, solutions-focused discussions with site personnel

• Act as a key liaison between field teams, vendors, and investigators, ensuring alignment, shared purpose, and continuous knowledge transfer

• Partner closely with field team colleagues to elevate the investigator and site experience, ensuring seamless collaboration and improving enrollment outcomes and Investigator relationships

Country / Regulatory Engagement (where applicable)

• Represent Investigator Engagement with regulatory agencies, ethics committees, and national research organizations in countries/territory

• Influence the clinical trial ecosystem to improve regulatory agility and operational feasibility

• Ensure that local requirements are translated into compliant, efficient trial execution and that sponsor’s internal processes reflect evolving country landscapes

• Partner with leadership to identify and align regional initiatives and contribute to enterprise-wide clinical development suc