Associate Director or Director, Bioanalytical

Who we are:

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn. 

 

How we work:

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

 

How you’ll contribute:

As the Associate Director or Director, Bioanalytical you will work within the Bioanalysis group and on project teams to design, implement, and execute bioanalytical solutions to advance Kymera’s projects from lead optimization, IND-enabling, and into clinical development. You will leverage your leadership and scientific expertise to deliver cutting-edge bioanalytical work-blocks to meaningfully advance our pipeline. You will thrive in a highly matrixed, mission focused, and dynamic environment.

• Serve as the bioanalytical (BA) project lead and effectively interface with internal (Pharmacology, Safety, Clin. Pharm, Clin. Ops, DMPK, Quality) and external CRO partners to deliver bioanalytical strategy and execution in support of Kymera’s project portfolio Will serve as the primary point of contact both internally and externally, with a strong emphasis on building and maintaining internal relationships and effective communication.
• Identify and maintain relationships with high quality CROs to meet project demands for both discovery and development BA support
• Effective and timely execution in collaboration with CROs: Develop and validate bioanalytical methods for preclinical and clinical study support. Ensure excellence in study stewardship, bioanalytical data delivery, and analysis
• Conduct detailed review and ownership of all bioanalytical data and reports (GLP and non-GLP)
• Adhere strongly to all quality standards, and collaborate with QA (Quality Assurance) to ensure compliance with all bioanalytical workflows
• Author and review relevant sections of regulatory and internal documents

 

Skills and experience you’ll bring:

• Master or PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences or related disciplines with 10+ years (with MSc) / 7+ years (with PhD) of relevant experience in the pharmaceutical industry or at a Bioanalytical CRO.
• Extensive hands-on experience in small molecule regulated (GLP) and discovery bioanalysis with deep understanding of LC-MS/MS method development, troubleshooting and qualification/validation.
• Deep knowledge of regulatory guidelines (FDA, EMA, ICH M10 etc.) for Regulated Bioanalysis and GLP practices is critically required.
• Proven track records of scientific achievements in LC-MS quantitative bioanalysis as evident by publications and presentations
• Experience of delivery of bioanalytical work blocks via GLP and non-GLP CROs and expertise in managing CROs to support GLP and clinical studies to help advancing projects to different stages
• Proven track record of working in cross-functional project teams in Discovery, Preclinical [GLP & non-GLP], and Clinical Bioanalytical study support
• Strong analytical, organizational, and communication skills

 

                                                                                                                                                                                  

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment.  All a