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Senior AI-ML Engineer

Mayo Clinic
United StatesRemotefull_timeVerifiedPosted 10 Aug 2026

About the role

AI/ML Engineers at Mayo Clinic play a pivotal role in the union of data, systems, and computer sciences. They work closely with a multidisciplinary team, including clinicians, user experience designers, product managers, IT professionals, and external partners, to develop and deploy effective, efficient, and ethical AI/ML solutions into clinical practice to enhance patient care and operational efficiency.
 

As a Senior AI/ML Engineer, you may work on the full spectrum of the AI life cycle from ideation to production. You understand the clinical environment well, including workflows, challenges, and requirements of healthcare providers and patients. You will leverage advanced techniques in AI/ML to analyze vast amounts of healthcare data, including patient records, medical imaging, and genomic information, to develop AI solutions that meet clinical needs and are integrated smoothly into clinical processes. You will develop, integrate, and standardize software components and create, maintain, and follow quality system procedures. You will guide the engineering of systems that are pivotal to developing and deploying these solutions, which encompass everything from design requirements, development, component creation, verification, non-clinical validation, and risk mitigation to ensure our digital health technology products meet and exceed regulatory requirements and setting new benchmarks for safety and effectiveness in clinical settings. Your expertise will also extend to facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines. 
This role is instrumental in providing consultative services to departments and divisions, offering insights into complex business problems. Your ability to communicate complex findings in easily understandable terms to non-technical users will bridge the gap between sophisticated AI technologies and clinical applications.

•   Leading component design, development, integration, and standardization to create AI-driven solutions that seamlessly integrate into clinical practice to enhance patient care and clinic operations.
•   Collaborating with a multidisciplinary team, including clinicians, user experience designers, product managers, and IT professionals, to understand user needs, workflows, and clinical requirements and assess feasibility. Translating user feedback and requirements into design concepts and usability specifications for AI solutions.
•   Leveraging machine learning techniques such as deep learning, natural language processing, computer vision, large language models, etc., to lead the design, development, and deployment of end-to-end AI solutions for healthcare applications.
•   Establishing evaluation methodologies and performance metrics to assess AI solutions' effectiveness, usability, and impact in real-world healthcare settings.
•   Explaining data analysis results to guide strategic choices and clarify complex insights for non-technical users to connect AI technologies and clinical applications. 
•   Overseeing the engineering of systems crucial for developing and deploying AI solutions.
•   Facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines.
•   Contributing to implementing the best practices and standards for AI development and deployment methodologies, tools, and platforms.
•   Providing mentorship, guidance, and technical leadership to junior engineers within the AI enablement team. 
•   Providing consultative services on areas of expertise to clinical work units or AI product teams, offering insights and strategies to address complex business problems.
•   Providing training and education to healthcare staff on AI tools and technologies.
•   Contributing to developing new AI methods and technologies that can advance the state-of-the-art in healthcare AI. 

This position is a combination of remote and on-site work; individual must live within a 100 mile driving distance to the Arizona, Jacksonville or Rochester Mayo Clinic campus.

**Visa sponsorship is not available for this position.  Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.

 

•   A master’s degree in engineering, computer science, mathematics, health science, or a related field with 4 years of experience, a bachelor’s degree with 6 years of experience. 
•   Extensive experience applying AI and machine learning in production healthcare environments or similar highly regulated or technology focused industries, showcasing an understanding of healthcare technology.
•   Demonstrated leadership in managing complex projects, with a proven ability to navigate intricate project requir

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Company

Mayo Clinic

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