Senior Manager, DEC Clinical Systems Operations (Remote)

If you are a current Jazz employee please apply via the Internal Career site

Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit www.jazzpharmaceuticals.com for more information.

Job Description

Jazz Pharmaceuticals’ Digital Enterprise Capabilities (DEC) organization is seeking a seasoned and delivery-focused Product/System Owner to manage the digital product line supporting Clinical Development Operations across the clinical trial lifecycle. This role is accountable for the ongoing lifecycle management and optimization of existing GxP-compliant systems supporting critical Clinical capabilities - including trial planning, study start-up, execution, data analysis, and study close-out. In addition, this role will support the delivery of new technology solutions aligned with Clinical capabilities.

As a member of the DEC R&D team, this role collaborates closely with the respective DEC R&D Business Partner (Capability Lead) - who defines digital strategy, capability roadmaps, and prioritizes demand – as well as the R&D business capability and process owners, quality, and other product delivery team roles to converts strategic priorities into actionable delivery plans and ensures reliable, compliant, and high-performing systems across the Clinical portfolio. This role leads the system release planning, oversees change control and validation activities, manages vendor relationships, and supports inspection readiness and operational excellence. This role is critical to advancing Jazz’s clinical technology ecosystem and delivering sustainable value across the clinical development lifecycle.

Essential Functions

• Partner with Clinical Development Operations business capability owners and DEC R&D Business Partners to ensure ongoing alignment, enhancement, and lifecycle management of capability-aligned digital systems supporting key clinical capabilities (e.g., trial planning, CTMS, EDC, site and investigator management).

• Collaborate across Jazz Clinical business functions, DEC product teams, and external vendors to manage day-to-day system operations and ensure business continuity.

• Own the backlog, execution of change control and validation activities in compliance with Jazz’s GxP, SDLC, and change management standards; ensure seamless coordination with business stakeholders for impact assessments, testing, and rollout.

• Maintain and continuously improve operational system documentation, including validation packages, configuration records, SOPs, and test scripts for both GxP and non-GxP systems.

• Drive issue resolution and technology optimization in partnership with vendors, product managers, and clinical capability leads, ensuring technology solutions are harmonized with evolving business processes.

• Plan and lead core system ownership responsibilities, including user access reviews, system performance monitoring, upgrade planning, system health checks, disaster recovery testing, and license and vendor contract management.

• Support product roadmapping and release planning by providing input on system enhancement opportunities, business value drivers, and technical feasibility.

• Manage aspects of system operations and smaller-scale projects, including scope definition, resource planning, timelines, and budget tracking in collaboration with product and portfolio teams.

• Ensure alignment with Jazz Quality and Compliance functions to uphold the appropriate level of validation, risk mitigation, and operational control across the system lifecycle.

• Facilitate the operationalization of newly implemented systems by collaborating with DEC Business Partners/Capability Leads and ensuring a smooth transition from project delivery to steady-state support.