Senior Principal Scientist, Translational Immunology

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Immunology and Cardiovascular Thematic Research Center (ICV TRC) at BMS is one of the fundamental Research units delivering therapeutics to patients. Our mission is to create transformative medicines of tomorrow based on the cutting-edge science of today. We leverage BMS’s internal invention engine that includes industry-leading expertise in small molecule chemistry, protein biotherapeutics, cell therapy, protein degradation, nucleic acids, and other therapeutic modalities.

Here, you will get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma. 

Position Summary

The Translational Early Development (TED) group within the ICV TRC seeks to understand disease pathophysiology to enable patient selection and stratification in clinical trials and develop critical assays to evaluate target engagement and pharmacodynamics of our new drugs in patients.

We are seeking a talented and highly motivated translational immunologist with strong leadership skills to join our team as Senior Principal Scientist.

Position Responsibilities

In the role as a Senior Principal Scientist within Translational Early Development, the ideal candidate:

• Works independently on most deliverables using knowledge and work experience

• Presents supportive arguments for highly complex ideas and projects to internal governance bodies and external stakeholders in a way that persuades them to adopt a different point of view, when appropriate

• Leads initiatives related to continuous improvement or development of new approaches and technologies within or across functions

• Encourages use of experimental innovative approaches within department

• Proactively fosters relationships across disciplines and participates in the decision-making process for completion of team goals

• Represents the TED team on multi-disciplinary project teams and accountable for identifying and delivering on translational needs

• Supervise generation of supportive data for translational plans that enable biomarker plans implementation in early clinical trials (including patient segmentation hypotheses, target engagement and phamacodynamic assays)

• Possibility to lead academic collaborations within BMS

Experience

Basic Qualifications:

• Bachelor’s Degree and 10+ years of academic and / or industry experience

Or

• Master’s Degree and 8+ years of academic and / or industry experience

Or

• Ph.D. and 6+ years of academic and industry experience

• 2+ years of leadership experience

Preferred Qualifications:

Requires comprehensive knowledge of principles, concepts and methodologies within drug discovery, development or production

• Ph.D. or equivalent advanced degree in immunology and 6+ years of academic and industry experience and 2+ years of leadership experience

• Deep knowledge of human immunology and immune-mediated diseases

• Experience in mining large datasets, either independently or in collaboration with computational biologists to understand disease pathophysiology and/or establish patient segmentation hypotheses

• Significant focus on cellular assay development for mechanistic characterization, and assessment of target engagement and/