Senior Principal AWS Cloud Architect

Career Category

Information Systems

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Principal AWS Cloud Architect

What you will do

Let’s do this. Let’s change the world. In this vital role you will serve as a technical visionary and hands-on technical leader for the design, development, and evolution of our enterprise-grade Amgen Cloud Platform. This role is pivotal in driving our cloud-first strategy by delivering secure, scalable, and high-performance cloud platform to power global research, manufacturing, and digital products.

As a Senior Principal Architect, you will influence platform design decisions, coach engineering teams, and define best practices while remaining deeply hands-on with AWS services and infrastructure as code.

Key Responsibilities:

• Lead the architecture and technical direction of the Amgen Cloud Platform on AWS.
• Define and enforce cloud-native architecture standards, patterns, and reusable components.
• Build scalable, secure, and compliant landing zones using AWS Control Tower, Organizations, SCPs, IAM, etc.
• Collaborate across security, data, DevOps, and application teams to design integrated solutions.
• Drive adoption of Infrastructure as Code (IaC) using tools like Terraform or AWS CDK.
• Evaluate and introduce emerging AWS services and architectural innovations into the platform.
• Provide architecture governance, design reviews, and mentorship to engineers and junior architects.
• Troubleshoot and resolve complex issues in cloud-native deployments and enterprise integrations.
• Contribute to Amgen’s cloud roadmap, reference architectures, and architectural principles.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The AWS Architect professional we seek is a problem solver with these qualifications.

Basic Qualifications:

Doctorate degree and 3 years of Computer Science or Information Technology experience

Or

Master’s degree and 5 years of Computer Science or Information Technology experience

Or

Bachelor’s degree and 7 years of Computer Science or Information Technology experience

Or

Associate’s degree and 12 years of Computer Science or Information Technology experience

Or

High school diploma / GED and 14 years of Computer Science or Information Technology experience-

Preferred Qualifications:

Must-Have Skills:

• 14+ years of experience in IT with 8+ years of AWS architecture and engineering.
• Demonstrated expertise in designing enterprise-scale platforms on AWS (multi-account, multi-region, secure).
• Solid command of core AWS services: EC2, S3, Lambda, ECS/EKS, VPC, IAM, KMS, CloudFormation/Terraform, Control Tower, Config, GuardDuty, etc.
• Deep knowledge of networking, security, and identity in AWS (VPC peering, PrivateLink, Transit Gateway, SCPs, IAM Roles & Policies).
• Strong hands-on expertise in Infrastructure as Code (Terraform or AWS CDK preferred).
• Experience with CI/CD pipelines, preferably using GitLab, or similar.
• Demonstrated ability to lead architectural design sessions, influence technical direction, and mentor teams.
• Solid understanding of compliance and security standards (e.g., HIPAA, GxP, NIST, CIS Benchmarks).
• Experience leading Well-Architected Reviews and aligning designs with AWS standard methodologies.
• Good communication and collaborator engagement skills.

Good-to-Have Skills:

• AWS Certified: Solutions Architect – Professional, or other specialty certifications.
• Experience with Kubernetes (EKS), serverless patterns, and event-driven architectures.