Jobs and Careers
MS

Principal Scientist, Early Development Chemistry, Small Molecule Process R&D

MSD
United StatesRemotefull_timeVerifiedPosted 3 Dec 2025
💰 $267,200/yr($169,700/yr$267,200/yr)

About the role

Job Description

Principal Scientist, Early Development Chemistry, Small Molecule Process R&D


Nature and Scope of Position:

Reports to the Early Development Chemistry Lead within the External Capabilities group of Small Molecule Process R&D,
our Research & Development Division. Responsible for the work of teams of scientists at our external partners, the role provides daily scientific oversight and real-time problem-solving in the areas of synthetic route design, scouting, optimization, and development, and API deliveries in support of our Company's
small molecule pipeline.

Collaborates effectively with Process Chemistry, Discovery Process Chemistry, Enabling Technologies, Chemical Engineering R&D, Analytical R&D, Quality, and other
our Company's partner groups to provide innovative and practical solutions to synthetic chemistry and development problems and ensure successful API deliveries under tight timelines. 

 

Must have deep subject matter expertise in synthetic chemistry and broad experience in general drug development.   As a scientific leader in SM PR&D, the incumbent is expected to establish a broad internal network, influence a diverse portfolio of programs both technically and strategically, and mentor young scientists within SM PR&D.

 

Builds and maintains strong working relationships with both management and scientists at our strategic external partners.  Promotes a culture of scientific excellence, trust, collaboration, quality, safety, and compliance that extends beyond our Company's team and into partner organizations. Refined communication, negotiation, influencing, and relationship management skills are essential for establishing partnerships in diverse geographies and cultures.


 

Qualifications:

 

Education Requirement:

  • Ph.D. in Synthetic Chemistry.

Required:

  • 6+ years of pharmaceutical industry experience in synthetic chemistry and demonstrated ability in leading and inspiring dynamic teams. 

  • Must have a strong track record of delivering results via innovation and fearless problem-solving.

  • Have experience in driving the supply strategy and science of new modalities

  • Excellent interpersonal, communication, negotiating, influencing, and collaboration skills. 

  • Must be recognized in the pharmaceutical industry through publications/presentations for subject matter expertise. 

  • Travel: Yes, 25% of the Time.

Required Skills:

Academic Presentations, Academic Presentations, Accountability, Bioconjugation, Chemical Biology, Chemical Engineering, Chemical Physics, Chemical Technology, Collaborative Communications, Computational Chemistry, Creativity, Data Analysis, Drug Development, High-Throughput Experimentation (HTE), Innovation, Machine Learning (ML), Medicinal Chemistry, Negotiation, Organic Synthesis, Outcome-Driven Innovation (ODI), Pharmaceutical Microbiology, Process Chemistry, Professional Networking, Project Leadership, Quality Management {+ 5 more}

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.  As a federal contractor, we comply with all affirmative action r

Apply for this role

Generate a tailored application kit with a matched cover letter, interview prep, and CV highlights — in under 60 seconds.

Apply Now →Generate Application Kit

Free account required — sign up in 30s

Company

MSD

View company profile →