Senior Information Security Engineer

At Adaptive, we’re Powering the Age of Immune Medicine.  Our goal is to harness the power of the adaptive immune system to transform the way diseases are diagnosed and treated.

As an Adapter, you’ll have the opportunity to make a difference in people’s lives. With Adaptive, you’ll create a career highlight through collaboration with bright, curious colleagues working at the apex of innovation and application.

It’s time for your next chapter. Discover your story with Adaptive.

 

Position Overview

The Senior Information Security Engineer is responsible for designing, building, and owning the security systems and controls across Adaptive’s environment.  This role focuses on developing scalable, effective solutions that reduce risk and improve the organization’s ability to prevent, detect, and respond to threats.

This role is expected to build and own security capabilities end-to-end from initial design through production operation and continuous improvement.

As part of the Information Security team, this role partners closely with Security Operations and is responsible for building and improving the systems they rely on.  The ideal candidate is a hands-on engineer who can operate across domains, work with imperfect data, and drive practical improvements in a dynamic environment.

Key Responsibilities and Essential Functions

Security Engineering & Control Implementation

• Design, implement, and improve security controls across cloud, endpoint, and application environments
• Evaluate and integrate security tools and technologies to improve coverage and effectiveness
• Identify gaps in existing controls and drive remediation
• Own control effectiveness and continuously improve based on real-world outcomes

Detection & Telemetry

• Own and improve detection logic across key security systems in partnership with Security Operations
• Co-own detection signal quality with Security Operations, continuously refining signal, reducing noise, and eliminating blind spots
• Design and maintain security telemetry pipelines, including log ingestion, normalization, and data quality
• Improve logging and visibility across systems to enable effective detection and response

Secure Development & System Integration

• Partner with engineering teams to integrate security into the software development lifecycle
• Define and implement security requirements for applications, infrastructure, and CI/CD pipelines
• Support secure design and architecture decisions through practical implementation

Automation & Tooling

• Build automation and integrations to improve the scalability and efficiency of security operations
• Leverage scripting and APIs to reduce manual work and improve consistency
• Develop systems that enrich, correlate, and operationalize security data

Continuous Improvement

• Use insights from incidents, vulnerabilities, and operational metrics to improve security systems and controls
• Contribute to evolving security standards, engineering practices, and technical direction

Position Requirements

• Bachelor’s degree and 7+ years of relevant experience, or equivalent practical experience
• Hands-on experience building and implementing security controls or systems in cloud, SaaS, or modern infrastructure environments
• Experience working with structured or semi-structured data and building systems that process and analyze that data
• Experience in one or more of the following areas: detection engineering, security telemetry/logging, vulnerability management, endpoint security, or application security
• Strong scripting or programming skills (e.g., Python), with experience building automation or data processing workflows
• Experience working with APIs and integrating systems
• Experience debugging and improving complex systems in production environments
• Solid understanding of security fundamentals (authentication, authorization, networking, common attack patterns)
• Ability to work cross-functionally and drive technical solutions in a dynamic environment

Preferred Qualifications

• Experience designing or implementing SIEM or logging pipelines
• Experience improving vulnerability management programs beyond basic scanning
• Familiarity with cloud environments and modern infrastructure patterns
• Experience in regulated environments, particularly medical devices or clinical laboratory (e.g., HIPAA, SOC 2, ISO 27001)

Working Conditions

• Administrative work in a home/office environment.
• Regular weekday work h