Senior Director, Project Management Office (PMO)

Senior Director, Project Management Office (PMO)

Location: Valencia, CA (Hybrid role)

Are you a strategic leader with a passion for driving enterprise transformation and execution excellence? We are seeking a Senior Director, Project Management Office (PMO) to lead and evolve our enterprise PMO, ensuring the successful delivery of strategic, operational, regulatory, and transformational initiatives across a global organization.

Reporting to the Vice President, Business Transformation & PMO, this role will serve as a trusted partner to executive leadership, driving portfolio governance, organizational prioritization, resource optimization, and project execution excellence. The ideal candidate brings a proven track record of PMO leadership, business transformation, and influencing outcomes within complex, matrixed environments.

What You'll Do

• Lead enterprise portfolio governance processes, including project prioritization, approval frameworks, portfolio reviews, and executive steering committees.
• Establish and continuously evolve PMO standards, methodologies, governance practices, and project delivery frameworks that drive consistency and accountability.
• Provide oversight of critical strategic initiatives, ensuring projects are executed effectively with strong risk management, stakeholder alignment, and predictable outcomes.
• Develop executive-level reporting, dashboards, KPIs, and portfolio analytics that enable data-driven decision-making and organizational transparency.
• Lead enterprise resource planning and capacity management processes to optimize prioritization, sequencing, and utilization of organizational resources.
• Partner with executive leaders to evaluate portfolio performance, identify risks and dependencies, and recommend strategic adjustments to maximize business value.
• Drive continuous improvement initiatives that enhance project delivery capabilities, governance maturity, and organizational effectiveness.
• Build, lead, and develop a high-performing PMO team while coaching project managers and business leaders on best practices in portfolio and project management.
• Support enterprise transformation initiatives and organizational change efforts that improve business performance and execution excellence.

What You'll Bring

Education

Required

• Bachelor's degree in Business, Engineering, Life Sciences, Management, or a related field

Preferred

• MBA or other advanced degree

Certifications

Preferred certifications include:

• PMP
• PgMP
• PMI-ACP
• Prosci
• Other project, program, or change management certifications

Experience

• 12+ years of progressive experience in project management, program management, portfolio management, PMO leadership, or business transformation
• Proven experience leading enterprise PMO functions within complex, matrixed organizations
• Experience building and developing PMO teams and project management professionals
• Demonstrated success implementing governance frameworks, prioritization models, and delivery standards
• Experience leading cross-functional strategic initiatives and organizational transformation programs
• Strong executive communication and stakeholder management experience

Skills & Competencies

• Strategic thinker with strong business and financial acumen
• Expertise in project, program, and portfolio management methodologies
• Exceptional leadership, influencing, and relationship-building skills
• Strong decision-making abilities with a data-driven approach
• Experience managing enterprise resource planning and organizational capacity
• Ability to lead through ambiguity, complexity, and organizational change
• Continuous improvement mindset with a focus on execution excellence and measurable outcomes
• Proven ability to influence senior leaders and align stakeholders without direct authority

Nice to Have

• Experience implementing enterprise portfolio management tools such as OnePlan, Smartsheet, Jira, Planview, or similar platforms
• Experience within medical device, life sciences, healthcare, or other highly regulated industries
• Experience leading PMO transformations and enterprise change initiatives

A minimum of 200Mb/sec download and 10Mb/sec upload speed internet connectivity is required to support any remote/hybrid employee functionality