Global Head of Research & Biomarkers - Vaccines

Job Title: Global Head of Research and Biomarkers - Vaccines

Location: FR / Marcy-L' Etoile

ABOUT THE JOB

Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization. Sanofi is a global biopharmaceutical company focusing on human health transforming scientific innovation in healthcare solutions. At Sanofi, we innovate in immunology, rare diseases & prevention. 

Sanofi Pasteur has been a leader in the vaccine industry for over 100 years. We are building a world in which no one suffers or dies from a vaccine preventable disease. We produce more than 1 billion doses of high-quality vaccines each year and save over 3 million lives worldwide. Sanofi is embracing the digital revolution. Today we incorporate big data, machine learning and advanced analytics into R&D, evidence generation, commercial operation and manufacturing. 

mRNA technology stands at the forefront of these scientific breakthroughs. In an ever-evolving healthcare landscape, we recognize mRNA's transformative potential to revolutionize how we prevent and treat diseases, making innovative solutions accessible to more people, faster than ever before.

That's why we've established our mRNA Center of Excellence. With an annual investment of €200m and a dedicated team of 500+ experts, we built an integrated end-to-end mRNA platform that brings together R&D, digital capabilities, and CMC expertise under one roof.

Bring your ambition and optimism and join us on our journey to discover and deliver transformative medicine to patients through the advancement of our cutting-edge mRNA technology!

ABOUT THIS ROLE 

In this role, the CTO, Global Head of Research & Biomarkers will be overseeing the overall end to end COE Research group covering pDNA, mRNA & Delivery (including Lipids discovery, associated synthesis) research teams and capabilities supporting Sanofi ambition in the field of therapeutic and prophylactic approaches serving unmet medical needs. 

Additionally, the CTO, Global Head of Research & Biomarkers will oversee a best-in-class mRNA Biomarker platform team based in France and Orlando, with the aim to: 

• Maximize efficacy and safety of LNP-mRNA through deep molecular and cellular immune profiling, 

• Deciphering the impact of the LNPs components on immune innate response as well as overall humoral and cellular immunity,

• A such, we will gain confidence in mRNA-based technology performance prediction. 

Overall, the Research and Biomarker Team will drive platform evolution and optimization through innovation in mRNA/LNP Design in prophylactic & therapeutic areas and will collaborate closely across the R&D team (Ag Design, Immunology Group, Clinical Development…) and project teams to support development candidates. 

As executive leader of the organization, the CTO, Global Head of Research & Biomarker is providing the best environment and support to project teams and scientists, enhance excellence in Science & Innovation in collaboration with key internal and external partners.

As site head, you will be in charge to provide local leadership and operational guidances to site, being a major contributor in both the transformation of the R&D Vaccine organization. In close collaboration with R&D Functions (Ag Design, Immunology…), you will establish the framework and coordinates activities necessary for the site to deliver on its share of global R&D milestones and strategic priorities. You will work on 3 main areas: operational, people, and ecosystem that promote changes and foster ways of working to ensure Vx R&D becomes the best organization for innovation in the region including developing collaboration with Genomic Medicine Unit located close by.

KEY RESPONSIBILITIES: 

Lead, engage, drive and develop a team whose mission is to conduct research on mRNA, LNP and formulation (Delivery) design for various applications and specific routes of administration, including: 

• The support for the targeted disease sc