Senior Scientist, Physical Chemistry II

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

AbbVie is looking for a talented scientist with strong expertise in the biophysical characterization of peptides to join our team in Lake County, Illinois. This scientist, using NMR spectroscopy, computational methods, and other biophysical tools, will play a central role in the discovery and advancement of peptide-based therapeutics across a variety of disease areas. As an integral member of our team, you will drive projects and collaborate across various functions within our Discovery organization. Initial efforts will involve the development of robust workflows aimed at conformational evaluation of peptides, both free in solution, and when bound to a target protein. Success in this position requires a solid foundation in NMR spectroscopy and related computational methods, strong collaborative skills, and excellent communication skills. This role will require a high level of technical proficiency combined with a proactive approach to solving key problems and answering key questions related to peptide-based drug discovery.

Key Responsibilities:

• Develop NMR experimental and computational workflows aimed at peptide resonance assignment and the determination of both free and protein-bound peptide conformations
• Integrate these workflows into overall efforts aimed at discovering and advancing peptide-based therapeutics
• Serve as a technical expert with respect to peptide biophysical analysis, especially NMR
• Work closely with project teams to identify and solve key questions within the domain of peptide-based drug discovery
• Stay ahead of scientific discoveries to integrate valuable insights into evolving strategies for peptide-based drug discovery especially with respect t