Director, Clinical Operations, Vendor Contracting Relations

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

This is a unique opportunity for a Clinical Operations Professional who has innate leadership and organizational skills, technical expertise in clinical oncology drug development in an industry setting, and experience in organizing and overseeing key clinical trial systems. As a director you will be responsible for operational design, team structure of and accountable for the oversight and general execution of contractual and budget negotiation, clinical RFPs and support finance business systems, build vendor relationships to contribute to the highest quality with on time delivery of RevMeds clinical studies.

• Establish a governance, structured approach to Clinical Vendor contracting/budgeting.

• Develop and establish cross functional relations with development operations teams (clinical, DM, Biometrics, safety, regulatory, quality) as well as Finance and Legal to define and review vendor contract proposals and budgets.

• Provide operational guidance to develop strategic Vendors and clinical research organizations relationships which will provide quality resources and solutions across RevMed clinical programs.

• Establish and develop request for proposal content in support of clinical studies and lead the vendor selection process on a study and portfolio basis.

• Contribute towards a governed, structured approach to review work orders, change orders and consulting agreements according to the scope of services requested.

• Accountable for templates with the clinical vendors which align to the best clinical practices and responsibilities.

• Enable collaborative and communicate effectively with all functional area representatives, in the project team environment as needed to ensure alignment across functions to support clinical programs.

• Contributes to oversight and manage a structured approach for Legal and Finance to review, amend and negotiate Master Service Agreements with vendors.

• Provide strategic contributions to QA and IT for completion of vendor qualification as required under SOPs.

• Accountable for overall vendor management of multiple clinical trials across all clinical study vendors.

• Contributes expertise to coordinate and ensure vendor agreements cover all operational activities for a successful clinical trial.

• Lead internal and external logistics and/all activities/services required to streamline execution of vendor agreements and purchase orders.

• Initiates, cultivates and maintains strong relationships with vendors and the study teams they support.

• Create and manage systems and processes required for seamless communication with the Clinical Stakeholders.

• Ability to identify critical path activities and articulate and mitigate risks to clinical trial conduct.

• Successful planning and deployment of Clinical Operations staff for project and non-project related tasks. Establish clear roles and responsibilities for team members and include opportunities to stretch skills and enable growth.

• Line management responsibilities include hiring, performance management, career development, and mentorship.

• Participate in and/or lead vendor governance activities for key CRO/vendor partners.

• Recommend and implement innovative processes to improve and impact clinical trial management and deliverables including contingency plans.

Required Skills, Experience and Education:

• Minimum of a BS, plus 10-15 years of experience in a finance and contract administration environment in a pharmaceutical, CRO/ biotech company or worked in a clinical operations setting with a CRO/Sponsor company Advanced degree desirable.

• Experience in evaluating, negotiating, and managing multiple successful relationships with partners, ability to set up milestones to track progress and collaborating with partners.

• Expertise in large, multi-site, Phase 3 clinical trials.

• Experience working in growing companies or departments that have created successful processes.

• Direct experience with vetting and