Director, Bioanalytical Development

Company Summary:

Laronde is pioneering a platform that offers a completely novel way of modulating human biology via Endless RNA™ (eRNA). eRNA is a uniquely engineered RNA that can be programmed to express diverse proteins inside the body. Laronde is rapidly scaling to support the development of multiple programs across many disease areas. ​

Laronde was founded in 2017 by Flagship Labs, the innovation foundry of Flagship Pioneering. Laronde has a highly collaborative, dedicated culture, driven to achieve our vision of “making eRNA an essential class of medicines to everyone, everywhere”. To learn more, please visit the company’s website at https://www.laronde.bio.

Position Summary:

We are seeking a Director of Bioanalytical Development to set strategy and lead the development of bioanalytical assays by providing leadership, scientific and technical expertise in support of Laronde's pipeline. This position will lead collaborations with external contract analytical testing organizations and provide support with the preparation of regulatory filings and correspondences. The incumbent brings enthusiasm, intellectual curiosity, scientific rigor and a desire to innovate breakthrough medicines.

Key Responsibilities:

• Responsible for establishing and managing a diverse range of bioanalytical assays and biological testing activities to enable fast and seamless preclinical development.
• Lead internal in vitro cellular pharmacology team in the development and execution of critical assay screening campaigns
• Lead method development and phase appropriate qualification / validation of bioanalytical assays as well as transfer of methods to contract testing laboratories (CTL).
• Responsible for CTL evaluation and selection. Participate in vendor audits, train personnel and lead troubleshooting and investigations for bioanalytical methods.
• Directly responsible for developing and reviewing assay protocols, SOPs and reports for bioanalytical methods.
• Responsible for preparing dossiers and data packages and providing input for interactions with regulatory agencies.
• Collaborate with cross-functional teams to prioritize and allocate resources for bioanalytical assay development and data generation.
• Develop the talent pipeline through recruitment activities and being a mentor, coach and educational resource across LARONDE.

Requirements:

• MS or Ph.D. in molecular biology, biochemistry, or related field
• 10+ years experience in bioanalytical development.
• In-depth knowledge of bioassay development and validation, with experience in immunoassays and/or mass spec based quantification assays.
• Detailed knowledge of drug discovery and development to apply independent judgement and direction to bioanalytical studies and the bioanalytical team.
• Demonstrated ability to build and maintain positive and collaborative relationships with management, peers, subordinates and externally with third-party contract organizations.
• Proven ability to work with a high level of integrity, accuracy and attention to detail.
• Strong organizational skills to maintain a high level of productivity, innovation and priority-setting to complete assignments on time and budget.
• Strong leadership and management skills, excellent verbal and written communication.
• Entrepreneurial, enjoys working in a fast-paced small-company environment.
• Ability to work successfully in a matrix environment, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively.

Laronde is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Laronde does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Laronde or its employees is strictly prohibited unless contacted directly by Laronde’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Laronde, and Laronde will not owe any referral or other fees with respect thereto