Senior Medical Director, Kidney Disease, Early Clinical Development CVRM

The Senior Medical Director will be focused on Kidney Disease and related conditions that impact kidney function. In this role, you will have the opportunity to work at the forefront of early clinical and translational research within CVRM. In a multidisciplinary environment, you will play a key role in progressing a rich and diverse pipeline of both small and large molecules in numerous active clinical programs.  

Who We Are 

In the Cardiovascular, Renal & Metabolism (CVRM) Translational Medicine & Clinical Development (TSCD) department, we are investigating the underlying factors contributing to CVRM disease progression using advanced scientific methodologies and data-driven drug discovery. In this context, we are evaluating a wide range of different drug modalities from our rich CVRM portfolio of compounds across kidney disease patient populations. 

TSCD is where science meets clinical drug development with a focus upon delivering innovative, early phase clinical studies and accelerating human target validation while collaborating closely with our late phase clinical development and regulatory colleagues who guide our pivotal phase 3 clinical studies. 

What You Will Do 

You will be responsible for managing and leading to  early phase I-II global clinical trials  and related clinical research projects for compounds that are targeting kidney disease, as well as serving as an expert on the design, conduct, monitoring, data interpretation, and reporting of these studies.

Additionally, you will work on cross-functional teams within our TSCD group and across the broader global CVRM organization that are framing our strategies and development plans for compounds that are targeting cardiovascular diseases such as Heart Failure, as well as major metabolic disorders, such as Type 2 Diabetes, Obesity, and Metabolic Dysfunction-Associated Steatohepatitis, given that these disorders intersect with chronic kidney disease and influence disease progression.  

Responsibilities include: 

•  Lead early Phase I–II global trials in kidney disease: clinical strategy, protocol design, study conduct, monitoring, data interpretation, and reporting, ensuring scientific integrity, patient safety, and regulatory compliance. 
• Provide clinical leadership to cross-functional teams; integrate preclinical insights (target selection, pharmacology, in vivo/in vitro data) into early clinical plans and seamless transitions to late phase development. 
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