Program Manager

Site: The General Hospital Corporation

 

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

 

Job Summary

The Division of Neuropsychiatry and Interventional Psychiatry at Mass General Brigham and Harvard Medical School integrates research, innovation, clinical care, and training across a large and dynamic clinical neuroscience portfolio.

Reporting to the Division Chief, the Program Manager for Research Operations will lead the execution and operational infrastructure of the Division’s research portfolio, ensuring that studies, grants, and scientific outputs progress reliably from initiation through completion.

This role serves as the operational backbone for research activities, building systems, enforcing timelines, and overseeing day-to-day research operations. The Program Manager partners closely with research staff, faculty, and institutional teams, ensuring high-quality, compliant, and efficient study execution within a structured and scalable operational framework.

 

. Human Research Operations & Team Leadership

• Oversee study execution across the full research lifecycle, including:
  • protocol development and study start-up
  • active study operations
  • participant enrollment and study visits
  • study closeout and reporting
• Directly supervise a team of research assistants and junior staff, including hiring, onboarding, supervision, task allocation, performance management, and professional development.
• Ensure appropriate staffing, coverage, and workload allocation across studies.
• Provide ongoing coaching and guidance to research staff to support high-quality study execution and day-to-day operational reliability across studies.
• Serve as the primary operational point of contact for study teams, resolving day-to-day issues and ensuring smooth coordination across projects
• Support preparation and coordination of administrative and regulatory components of grant applications, working with investigators and pre-/post-award teams to ensure completeness, alignment with study operations, and timely submission

2. Research Execution Systems & Infrastructure

• Develop and maintain systems to support research operations, including:
  • project and portfolio tracking tools
  • dashboards and reporting frameworks
  • SOPs and standardized workflows
• Define and implement metrics to monitor study launch, progress, recruitment, and performance
• Maintain structured dashboards and trackers that identify project status, upcoming milestones, risks, and dependencies, and ensure this information is current and actionable
• Build scalable infrastructure that can be adopted across the division

3. Project & Portfolio Execution

• Translate research priorities into structured work plans with:
  • timelines
  • ownership
  • deliverables
• Track progress across projects and ensure adherence to milestones and deadlines
• Identify delays, bottlenecks, and risks early and implement corrective actions
• Work closely with investigators and study teams to ensure alignment and execution
• Actively enforce follow-through and accountability across research workstreams

4. Regulatory Compliance, Governance, & Quality Oversight

• Oversee regulatory and compliance processes, including:
  • IRB submissions, amendments, and renewals
  • protocol deviations and reportable events
  • maintenance of required regulatory documentation
  • adherence to Good Clinical Practice (GCP) standards
• Implement and maintain quality and compliance systems across studies, including regulatory oversight, data quality assurance, and protocol adherence across studies
• Ensure compliance with institutional, NIH, and sponsor requirements
• Coordinate with institutional compliance and research administration offices
• Ensure research staff maintain required certifications and are appropriately trained in and adhere to Good Clinical Practice (GCP) standards and institutional compliance requirements; monitor compliance and address gaps as needed

5. Administrative Systems & Operational Support

• Delegate executi