Senior Manager, Quality Operations

<p><strong>Senior Manager, Quality Operations</strong></p> <p>Nurix Therapeutics is a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation therapeutics. Leveraging our proprietary DELigase platform, we design small molecules that harness the body’s own protein disposal system to selectively eliminate disease-causing proteins. Our pipeline spans oncology and immune-mediated diseases, and our team is united by a commitment to scientific excellence and meaningful impact for patients.</p> <p>We are a team of scientists, innovators, and problem-solvers committed to improving patient lives. We value integrity in everything we do — from the bench to the boardroom — and we foster an environment where every voice is heard and every contribution matters.</p> <p><strong>Position</strong></p> <p>The Senior Manager, Quality Operations is an important operational and technical contributor within the Nurix Quality organization, responsible for supporting the quality operations and GMP compliance activities that underpin Nurix’s clinical development programs. This role will partner closely with CMC teams, CDMOs, and internal stakeholders to ensure quality oversight across drug manufacturing, laboratory operations, auditing, and inspection readiness.&nbsp; Reporting to the Senior Director, Quality, the Senior Manager will execute essential quality systems activities including deviation management, change control, CAPA, batch record review, and audit support. This individual will demonstrate strong independent judgment, meticulous attention to detail, and the ability to collaborate effectively across functions in a dynamic, early to late clinical-stage environment where quality and program timelines are closely intertwined</p> <p><strong>Responsibilities</strong></p> <p><strong>Drug Manufacturing Quality Operations</strong></p> <ul> <li>Execute and support quality systems operations for clinical development, including document management, deviation management, change control, CAPA, training, and validation activities.</li> <li>Provide day-to-day quality oversight of CDMOs and contract laboratory operations, including review and approval of deviations, OOS/OOT investigations, batch records, specifications, sampling and testing plans, analytical methods, and lot disposition decisions.</li> <li>Review and approve development, process transfer, and validation protocols and reports; verify process data in support of CMC regulatory submissions (INDs and NDAs).</li> <li>Approve production-related activities including master batch records, change controls, stability study protocols and reports, and certificate of analysis reviews.</li> <li>Participate in CMO selection, commissioning, qualification, a