Senior Scientist I - Chemistry

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

The AbbVie Process Chemistry Chromatographic Separations Lab is actively seeking a Sr. Scientist I with experience in analytical and preparative chromatographic method development. Our team collaborates with colleagues across multiple disciplines, offering expertise in preparative chromatography to support a broad range of AbbVie R&D programs. We maintain and utilize specialized equipment for a variety separation tasks, including the purification of peptides, ADC drug-linkers, and chiral compounds, as well as the isolation of low-level small molecule API impurities. Additionally, the team is responsible for pilot-scale preparative purification, developing scalable purification processes, and overseeing their implementation under cGMP guidelines at AbbVie's North Chicago Chemical Pilot Plant. This role will contribute to the development of novel/advanced separations technologies and broader efforts to develop new process technologies for advancing the AbbVie pipeline, including the application of machine learning strategies.

We are looking for a highly motivated scientist capable of conceiving, implementing, and executing novel research and development projects. Ideal candidates will have hands-on experience developing chromatographic methods and troubleshooting complex separation challenges. Experience working with peptides is highly desirable, though not strictly required for application.

Key Responsibilities:

• Develop and execute purification processes to support the clinical development of potential therapies, including small molecules, antibody drug conjugates, and peptides.
• Routinely demonstrate scientific initiative and creativity in research and development activities to res