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Senior Scientist, Protein Engineering - Chemical Biotechnologies (Onsite)

MSD
United StatesRemotefull_timeVerifiedPosted 24 Sept 2024
💰 $175,300/yr($111,400/yr$175,300/yr)

About the role

Job Description

The Chemical Biotechnologies group within the Process Research & Development Enabling Technologies Department in Rahway, New Jersey is seeking a Senior Scientist to expand our capabilities to design and engineer proteins with novel functions. The mission of the group is to invent, develop, and implement biomolecules and biocatalytic processes to advance our company's pipeline and our impact on the scientific community. We view protein engineering as a key enabling technology in modern drug discovery and development.  We leverage computational modeling, advanced automation, and high-throughput screening to engineer novel proteins.  We are committed to developing new methodologies and technologies that enhance protein engineering and improve human health.  The group collaborates broadly within our Company, with academic leaders, and with industry partners to expand and accelerate the impact of protein engineering on human health.

In this role, the incumbent will contribute directly to the invention of novel proteins by guiding gene acquisition, designing and building high-quality DNA libraries, expressing large protein libraries, developing assays, and/or characterizing libraries using high-throughput screens and selections.  As part of project teams, they will collaborate across groups to develop novel solutions that solve complex problems.  They will develop engineering strategies, choose which engineered proteins to select as leads, and deliver biocatalysts and/or biotherapeutics with improved functions and properties.  They will give scientific presentations internally and externally, contribute to the overall strategy and direction of the group, and develop novel protein engineering technologies.  The successful candidate will join a diverse group of innovative scientists that are driving the next revolution in bioengineering. 

Minimum Requirements:

  • PhD, Postdoctoral in Molecular Biology, Biochemistry, Bioengineering, Synthetic Biology or a related field, as evidenced by published field-impacting research in which the applicant participated in the conception, execution, analysis, and drafting of the research.

  • Broad experience and knowledge in synthetic biology, biological engineering, protein design, and/or directed evolution.

  • Significant expertise in one of the following: molecular biology, biochemistry, biophysics, computational protein design, or metabolic engineering.

  • Demonstrated ability to work within a collaborative multi-disciplinary team environment.

  • Excellent communication and organizational skills.

Preferred Experience and Skills:

  • Experience engineering one of the following: novel biocatalysts, biosynthetic pathways, amino acid/peptide modifying enzymes, protein assemblies, and/or de novo proteins.

  • Experience with multiple strategies to create genetic diversity, multiple host organisms and/or cell free expression systems, and/or multiple high-throughput screening/selection methods.

  • Familiarity with one or more of the following areas are highly desired: next-generation sequencing, computational protein design, machine learning, microfluidics, and/or automation.

  • Experience with reproducible data analysis, for example using Python or R.

#EligibleForERP

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders).  Please understand that, as permitted by applicable law, if you have not been vaccinated against C

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MSD

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