Senior Manager, RIM Business Administrator & Data Steward

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

The Veeva RIM Business Administrator & Data Steward is responsible for the day‑to‑day business administration and data stewardship of the Veeva Vault RIM platform. This role ensures high data quality, consistent business use of the system, reliable reporting, and strong user support across the Regulatory Affairs community. The Senior Manager supports release and change activities, partners with Key Users, and helps sustain inspection readiness through strong documentation and process adherence. 

Key Responsibilities: 

Regulatory Data & System Management 

• Ensure data accuracy, completeness, and compliance with internal standards and global regulatory requirements. 

• Develop and maintain data models, controlled vocabularies, and metadata standards. 

• Monitor system performance and coordinate issue resolution with IT, business stakeholders and system vendors. 

Regulatory Operations Support 

• Support planning, tracking, execution and archiving global regulatory submissions. 

• Oversee the use of wizards, templates, and structured content within Veeva Vault to ensure consistent data entry and record creation. Manage email notification, renditions, jobs and vault loader. 

• Accountable for end user provisioning in RIM & other Regulatory affairs systems 

• Create and maintain standard dashboards/reports, support ad hoc reporting, trend operational metrics and recommend improvements. 

User Support & Key User Enablement 

• Provide first-line business support and triage in close collaboration with IT and Key Users. 

• Maintain Training Videos, Quick Reference Guides/FAQs. 

• Support onboarding of new end users.  

Release and Change Management Support 

• Support safe and compliant deployment of releases/changes (impact assessment, UAT test execution, change control evidence capture etc.). 

Compliance & Inspection Readiness 

• Maintain SOPs and work instruc