Senior Director, Development - Project Management

Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC® Discovery Engine platform to engineer proteolysis targeting chimeras, or PROTAC® targeted protein degraders, that are designed to harness the body’s own natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins.

In addition to its robust preclinical pipeline of PROTAC protein degraders against validated and “undruggable” targets, the company has three investigational clinical-stage programs currently enrolling: vepdegestrant for the treatment of patients with locally advanced or metastatic ER+/HER2- breast cancer; ARV-102 for the treatment of patients with neurodegenerative disorders, and ARV-393 for the treatment of patients with relapsed/refractory non-Hodgkin Lymphoma and potentially other lymphomas.

In April 2024, Arvinas entered into a transaction with Novartis, including a global license agreement for the development and commercialization of the clinical stage PROTAC® androgen receptor protein degrader ARV-766 for the treatment of prostate cancer. The transaction closed in May 2024.

#TeamArvinas is made up of approximately 450 passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company’s values and mission – to improve the lives of patients with serious diseases by pioneering therapies created with our revolutionary PROTAC® protein degradation platform. We’re really excited about the work we’re doing inside and outside of Arvinas, and think you will be, too. But don’t just take our word for it – learn more about life at Arvinas and what employees have to say.

For more information, please visit www.arvinas.com. 

  

Position Summary

The position leads project management for 2-3 Development programs portfolio and supports assets establishing a plan from CCN to FIH and beyond. The role will be a player coach and will lead project management for a few programs and mentor and guide other junior colleagues on PM best practices. The role will oversee establishing a team structure, resources, key stage gates, budgets, risks and plans for the assigned assets. We currently anticipate this role to serve as the PM lead for 2 Oncology assets. The role will also support and drive building out key infrastructure and processes for Project Management as a key leader in the organization interfacing with other aspects of the organization including Planning, Discovery and CMC when appropriate.

This position reports to the Head of Enterprise Project Management and Governance and will be a hybrid role in New Haven, CT.

 

Principal Responsibilities

Key responsibilities of this role include, but are not limited to:

• Partners with Development Team Leadership and teams in managing an integrated view about the assets, their key milestones, goals, budgets, risks, and plans.
• Partners with assigned planner and asset teams in creating and maintaining integrated cross-functional program plans, including development and assessment of scenarios and options, decision criteria, and internal and external cross-functional communication and stakeholder management strategies.
• Partners with Discovery teams and their leadership to support Clinical transition planning, engaging with key Development stakeholders to support downstream planning and engagement.
• Challenges teams to think about and anticipate risks, proactively manage risks and develop mitigation strategies.
• Manages core team and sub-team meetings as appropriate and accurately incorporates functional area objectives into overall devel