Scientist/Senior Scientist, Material Sciences

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

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The Protein, Bioanalysis, and Material Sciences (PMBS) group is part of the Precision Medicine, Bioanalytical and Translational Sciences (PMBATS) team. PMBATS leads internal and external bioanalytical and diagnostic research & development activities to support multiple disease areas of interest including hematological malignancies, inflammatory disease programs, neuroscience, cardiovascular, fibrosis, and solid tumor indications. The PMBATS group integrates scientific insights of multiple functions to provide innovative solutions that will make precision medicine a reality for the patients and health care providers we serve. 

The primary purpose of this position is to lead and conduct laboratory experiments for the biophysical characterization of protein reagents for use across multiple technology platforms, including but not limited to:  Flow cytometry, IHC, and immunoassays. In this role the individual will be responsible for collaborating and communicating across the organization to assure on-time delivery of high-quality characterized materials.

Responsibilities:

• Works independently with limited supervision to design, execute, and analyze laboratory experiments to assess the biophysical/binding properties of antibody and non-antibody protein reagents using BLI, SPR, and other technologies.
• Works independently with limited supervision to design and execute method development experiments for immunoassays.
• Work with limited supervision to perform conjugations/purification of antibody and non-antibody proteins.
• Works independently with limited supervision to interpret results, plan next steps, compile final data summaries, and present results to stakeholders.
• May lead projects and provide oversight of experimental design and data review for junior staff members.
• May lead scientific collaborations and/or contracted research as needed.
• Collaborate with internal stakeholders to understand project needs and relay information back to the group.
• May serve as a technical point of contact within the group.
• May lead innovation projects related to the biophysical characterization of protein reagents.
• Troubleshoots assay problems and instrument malfunctions. 
• Maintains required training per BMS standard operating procedures.
• Maintains and completes notebooks and other documentation as per departmental guidelines.
• Achieves objectives in a manner consistent with the BMS Behaviors
• May lead or contribute to writing and presentation of findings in the form of posters, publications, and oral presentations (internal and external)

Preferred Qualifications:

• Experience with of BLI or SPR
• Knowledge in the development and validation of regulated pharmacokinetic, immunogenicity, and biomarker immunoassays.
• Familiarity with MALDI-MS, HRMS, SEC, RP chromatography, and Protein concentration techniques.
• Familiarity with bioconjugation of antibody and non-antibody proteins.
• Familiarity with antibody and non-antibody protein generation.
• Knowledge of the drug discovery and development process.
• Good verbal and written communication skills and the ability to independently interpret and deliver results.
• Ability to effectively work across levels and functions with both internal and external stakeholders.  
• Excellent problem-solving skills.

Basic Qualifications:

For Scientist Level:

• Bachelor’s Degree with 5+ years of related industry experience
• Master’s Degree with 3+ years of related industry experience
• Ph.D. in related field with 0 ye