Vice President, Program Lead

Company Summary:

Ring Therapeutics Inc. is a privately held, early-stage biotechnology company pioneering a completely novel form of gene therapy by exploiting a family of naturally occurring commensal viruses to create the first redosable and targetable DNA medicines. This approach enables a powerful new class of tropic, persistent, non-integrating vectors that overcome the immunogenicity, and limited tropism of existing gene therapy vectors. Ring Therapeutics is leveraging this versatile technology to develop a broad pipeline of novel, targeted medicines for disease with high unmet medical need.

Ring Therapeutics was founded by Flagship Pioneering, focused on launching breakthrough companies based on internally conceived innovations and insights. Flagship Pioneering has created over 40 groundbreaking companies over the past fifteen years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Seres Therapeutics (NASDAQ:MCRB), Moderna (MRNA), Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Axcella Health (AXLA), Evelo Biosciences (EVLO), and Indigo Agriculture.

Position Summary:

We are seeking a highly experienced and dynamic individual to join our team as the VP, Program Lead. In this role, you will be responsible for leading the strategic planning, development, and execution of our gene and cell therapy programs. Your matrixed leadership of the cross-functional teams will identify new opportunities and ensure the successful delivery of our programs. This leadership role requires a deep understanding of the gene and cell therapy landscape, strong business acumen, and excellent communication skills. This position will report to the Chief Medical Officer and it will be based out of our Headquarters in Cambridge, Ma.

Key Responsibilities:

Platform Strategy and Leadership:

• Integrate two platform technologies into a single technology program driving toward the clinic
• Provide strong leadership to cross-functional teams and foster a collaborative and innovative culture
• Stay abreast of industry trends and emerging technologies to identify opportunities for innovation and competitive advantage
• Lead with an inclusive and collaborative approach that blends agile progress toward goals within a respectful environment

Program Development Oversight:

• Lead the design, planning, and execution of platform-based cell and gene therapy programs
• Collaborate with R&D, Clinical Development, Regulatory Affairs, and other relevant functions to ensure successful program development from preclinical through clinical stages
• Drive the development of program-specific strategies, including timelines, budgets, and milestones

Cross-functional Collaboration:

• Work closely with the executive leadership team to integrate platform strategies into the overall corporate strategy
• Foster strong partnerships with external collaborators, including academic institutions, research organizations, and industry partners

Regulatory Compliance:

• Ensure that all platform development activities adhere to regulatory guidelines and industry best practices
• Collaborate with Regulatory Affairs to prepare and submit necessary regulatory documentation
• Resource Allocation and Budget Management:
  • • Manage the budget for platform development activities, ensuring efficient allocation of resources
    • Identify opportunities for cost optimization and risk mitigation

 Qualifications:

• Advanced degree (Ph.D., M.D., or equivalent) in a relevant scientific discipline
• Minimum of 12+ years of experience in the biotechnology or pharmaceutical industry, with a focus on gene and cell therapy
• Proven track record of successfully leading and managing gene and cell therapy programs from Early-stage Development through IND and Commercialization
• Strong understanding of the gene therapy landscape (cell therapy a plus), including regulatory requirements, manufacturing processes, and clinical development
• Excellent leadership and team management skills, with the ability to motivate and inspire cross-functional teams
• Exceptional strategic thinking and problem-solving abilities, with a demonstrated ability to drive innovation and identify new opportunities
• Excellent communication and presentation skills, with the ability to effectively communicate complex scientific concepts to both technical and non-technical stakeholders
• S