Human Genetics Lead - Diabetes, Obesity and Complications

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Diabetes, Obesity and Complications Therapeutic Area (DOCTA) focuses on new therapeutic approaches for the treatment of diabetes, obesity and cardiometabolic diseases. Starting from an idea, we work with partners across Lilly to discover and develop novel biologic, small molecule and nucleic acid-based therapeutics. Our focus is the patient: by understanding the biology and pathophysiology underlying disease states, we aim to address the root cause of disease, and develop breakthrough therapies. We have one of the strongest pipelines in the industry and a track record of delivering impactful medicines that improve people’s lives.

We are seeking a transformative Human Genetics Lead - Diabetes, Obesity, and Complications within the DOCTA organization. This role will drive our human genetics research forward. We need a forward-thinking, passionate, and collaborative leader with deep knowledge of human genetics and metabolic disease biology. The Human Genetics Lead will build and lead a diverse team of in-house geneticists. You will establish a vibrant network with the external scientific community. Represent the Data Science and Computational Biology (DSCB) group and DOCTA both internally and externally. Partner with key opinion leaders and identify strategic alliance opportunities in human genetics and metabolism. Under your leadership, the Human Genetics group within DSCB will impact disease target identification, indication expansion, subpopulation classification, and disease mechanism understanding. Use Lilly’s large in-house datasets and disease state expertise to address scientific questions. Push the boundaries of scientific innovation. Work across research and clinical groups within DOCTA and Eli Lilly in one of the most exciting and dynamic fields of research today.

Are you interested in a unique opportunity to help build and advance a life-changing portfolio of medicines? Appy today to join Team Lilly!

Key Responsibilities:

• Provide scientific leadership and strategic vision in human genetics to position Lilly at the forefront of genetics for diabetes, obesity, and complications
• Build, lead, and mentor a diverse team with expertise in statistical/population genetics, genomics, and genetic epidemiology
• Develop and implement an innovative model for execution on strategic priorities, including managing internal hires, postdoctoral fellows, contractors, vendors, and strategic partners
• Design and implement a visiting scholar program for senior-level human genetics researchers
• Develop and implement strategies to optimally use public large-scale genetic and genomic resources. Integrate population-scale biobanks and genome sequencing initiatives with patient-derived data from clinical trials. Provide novel insights for Lilly’s portfolio.
• Align with DOCTA’s strategic priorities and drive data-driven innovative approaches to identify and validate novel therapeutic targets
• Spearhead cross-functional initiatives to translate genetic/genomic findings into actionable insights that inform drug discovery, biomarker development, and clinical trial design
• Lead ongoing and new strategic collaborations to access unique genetic data assets and amplify research capabilities
• Represent Lilly at scientific conferences and engage with the broader genetics/genomics community to stay at the forefront of innovation
• Partner with internal teams to evaluate external innovation opportunities and bring insights to aid decision making
• Interpret and clearly communicate results from genetic analyses. Develop scientific manuscripts, posters, and presentations. Communicate the group's vision and progress to internal and external partners.
• Implement industry-standard standard methodologies for scientific project execution and documentation (e.g., JIRA, Confluence, Git, code review, and other documentation tools)
• Accountable for the team’s development and documentation of reproducible pipelines for genetics analyses
• Perform hands-on execution of human genetic analyses as needed
• Foster a culture of scientific excellence, collaboration, and continuous learning within the human genetics and bioinformatics group and across the organization

Minimum Requirements:

• PhD or equivalent in