Director Pathologist Global Pathology – CVRM Therapy Area

Director Pathologist Global Pathology – CVRM Therapy Area

Are you a medical/veterinary pathologist with expertise in toxicologic or disease area pathology and wants to help us deliver safe and effective new medicines to patients? This is an exciting opportunity to join a team of highly skilled pathologists to continue to push the boundaries of science!

AstraZeneca is looking for a dynamic and experienced Medical/Veterinary Pathologist to support our work in the Cardiovascular, Renal and Metabolism (CVRM) disease area. This role is broad in scope and offers significant potential for professional development. You will be based in Gaithersburg, US.

Pathology works closely with the CVRM disease area scientists and the Safety Sciences organization, providing integrated support covering all aspects of efficacy and safety pathology to drive the design, selection and successful development of novel treatments for patients with cardiovascular, renal and metabolic diseases. The Global Pathology department works across Sweden, UK and US covering all aspects of pathology for all AstraZeneca disease areas. Pathology sits within Clinical Pharmacology and Safety Sciences (CPSS), which contains all non-clinical safety functions that support the entire AstraZeneca portfolio.

What you’ll do
As a Pathologist you will work closely with discovery safety specialists and toxicologists as well as disease area scientists, providing expert anatomic pathology support to multiple drug projects across all development stages. You’ll contribute to the design and assessment of investigative safety and efficacy studies, ensuring timely delivery of high-quality pathology data. The AstraZeneca portfolio is modality agnostic and you will get exposure to projects exploring small molecules, biologics, oligonucleotides, cell therapies and more. While most of your work will be in the CVRM space, you will also have the opportunity to support our global portfolio in the Respiratory & Immunology, Vaccines & Immune Therapies and Oncology therapy areas.

You will work closely with our expert team of Imaging & AI scientists, with access to state-of-the-art tissue imaging platforms, exploring multi-omics and AI to drive translational quantitative pathology. We rely on you to build effective cross-functional networks across Pathology, CPSS and Early CVRM and with a curious mind seek opportunities for collaboration on safety and efficacy (e.g. animal model development, multimodal and in vivo imaging, mechanistic toxicology and disease pathophysiology). You are exploring the external scientific community to identify novel opportunities and build positive relationships with leading academic groups in relevant areas. You are expected to provide a comprehensive view of translational safety and efficacy pathology and pathophysiology from animal to patient. 

Requirements

• MD or DVM Pathology degree

• Postgraduate pathology qualification (e g FRCPath, ESP, DACVP, DECVP or DJSTP).

•  A minimum of 5 years’ experience in either toxicologic pathology or in a diagnostic area relevant to cardiovascular, renal or metabolic disease that includes cross-species research.

• Genuine interest in providing broad disease area, discovery and toxicologic pathology support and acting as a pathology representative on multiple drug development projects.

• Strong familiarity with complementary data sets (e.g. clinical pathology, IHC, ISH, MSI); ability to integrate pathology findings with a range of traditional and novel endpoints and provide contextualized interpretation for project teams.

• Highly effective written and communication skills with the ability to clearly convey complex pathology data to a wide range of stakeholders.

• Willingness to embrace and champion the use of digital technology for all aspects of pathology and delivery of quantitative pathology data.

Desirable in the role

• PhD in a subject relevant to toxicologic pathology or cardiovascular, renal or metabolic disease.

• Strong scientific track record with publications in high quality journals post PhD.

• Broad cross-species toxicologic pathology expertise with experience of histopathological evaluation and/or peer review.

More information

If you are a medical/veterinary pathologist seeking a new challenge, please get in touch with Magnus Söderberg at magnus.soderberg@astrazeneca.com for an informal discussion about this exciting opportunity!

Why AstraZeneca?
At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to