Principal Scientist, Analytical R&D

Role Summary

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.

As a Principal Scientist (R5) in Drug Product Development Analytical (DPDA-Analytical R&D), you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be recognized as a technical expert and a significant scientific contributor. With your deep knowledge of the discipline, you will regularly contribute at the therapeutic area level and can represent the department on multidisciplinary teams.
 

You will perform qualitative and quantitative analyses of organic and inorganic compounds to determine chemical and physical properties during drug product development process. You will be entrusted with setting objectives and planning resource requirements for your project team.  You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience. You will undertake mentoring activities to guide team members.

It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

Responsibilities

• This colleague will be responsible for developing analytical strategies in support of several pharmaceutical drug products during all development phases, including supporting manufacturing process development, developing, validating and transferring analytical methods, designing stability studies for shelf-life assignments, and developing advanced control strategies.

• Proficient with a breadth of relevant methodologies such as, chromatography, dissolution, IR/Raman spectroscopy, mass spectrometry, particle size analysis and NMR, with expertise in one or more of these techniques. 

• Experience with working with solid or semi-solid sample matrices, organic samples or pharmaceutical samples will be an integral part of this role.

• Collaborates with colleagues and subject matter experts to assess the most appropriate analytical approach to support project activities, including use of computational predictive tools, modelling software and data visualization tools where appropriate.

• Through effective leadership, communication and collaboration with multidisciplinary team members, this colleague will have the opportunity to lead and be responsible for several projects, helping teams devise effective strategies for analytical requirements and controls.

• The candidate must be able to collaborate with and mentor peers as well as effectively interact with colleagues at all levels of the organization.

• Author relevant sections of global regulatory submissions in support of new drug approvals. They will also prepare technical reports, critically review data, and may evaluate new instrumentation and analytical techniques/approaches.

• Proficient with a wide variety of software and information systems and the curiosity and passion to continue learning in a dynamic environment.

Qualifications

• PhD degree in Analytical Chemistry or related field, with at least 4+ years pharmaceutical drug product development experience.

• Proven record of strong technical skills and scientific expertise in analytical method development and troubleshooting

• Experience with technologies focused on analysis of pharmaceutical drug products such as HPLC, LC-MS, dissolution, spectroscopy (UC, IR, Raman) etc.

• Understanding of critical quality attributes of complex formulated products

• Exemplary people skills and demonstrable leadership behaviors

• Demonstrated technical writing and presentation skills

• Preference for other analytical techniques of value such as particle size analysis, thermal methods, material characterization, forensic analysis etc.

  

PHYSICAL/MENTAL REQUIREMENTS

Routine computer use is anticipated

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

• Less than 10% travel anticipated

Additional Information

• Relocation support available.

• Work location assignment: On Premise

The annual base salary for this position ranges from $