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Product Manager, AI Platform & Partnerships

Manifold Bio
Boston or San Francisco, USAfull_timePosted 12 May 2026

About the role

<p><strong>Manifold Bio is a platform biotechnology company pioneering AI-guided <span class="pearl-hilighted-word" style="color: black;">protein</span> design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems. </strong>Using proprietary <span class="pearl-hilighted-word" style="color: black;">molecular</span> barcoding technology, we screen hundreds of thousands of <span class="pearl-hilighted-word" style="color: black;">protein</span> designs simultaneously in living systems, producing in vivo-validated datasets at a scale no one else can match. The datasets power our computational models, which leads to better drug designs, creating a flywheel that gets stronger with every campaign. Our team of <span class="pearl-hilighted-word" style="color: black;">protein</span> engineers, biologists, and computational scientists works across this full stack to pursue programs both internally and with leading pharma companies.</p> <p><strong>Position</strong></p> <p>Manifold Bio is seeking a Product Manager to serve as the internal product owner for our AI projects, leading the roadmap across key domains including <span class="pearl-hilighted-word" style="color: black;">protein</span> design, foundation models, reasoning models, agents, and infrastructure. This role covers both&nbsp; internal product management and liaising with AI / tech partners., Internal responsibilities include interfacing with the AI team and R&amp;D project managers to translate ambitious AI x <span class="pearl-hilighted-word" style="color: black;">biology</span> ideas into shipped internal products and platform capabilities. External responsibilities include developing and nurturing relationships with external AI teams and partners, with an opportunity to flex into business development and strategic transactions. This role works closely with our co-founders, AI/ML leadership, and BD team to turn cutting-edge capabilities into durable platform assets.</p> <p><strong>Responsibilities</strong></p> <ul> <li>Define the product vision, roadmap, and success metrics for Manifold’s AI platform capabilities, including <span class="pearl-hilighted-word" style="color: black;">protein</span> design, foundation models, and agents</li> <li>Translate internal R&amp;D and AI x <span class="pearl-hilighted-word" style="color: black;">biology</span> ideas into concrete requirements and run the operating cadences that drive decisions and accountability</li> <li>Own Manifold's strategy for engaging the AI ecosystem; decide which partners to prio

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Manifold Bio

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