Sr. Technical Program Manager, Infrastructure Rationalization

The Role:

Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of infrastructure (cloud and on-prem) rationalization and AI-readiness initiatives at Moderna globally. We’re looking for someone with a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise.  

Here’s What You’ll Do

• Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting 

• Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process 

• Build processes, templates, and structure, or leverage existing ones as appropriate 

• Manage vendors, schedule, scope, and cost 

• Measure program success (or lack thereof) and risks using data and facts 

• Provide balanced risk remediation strategies and recommendations and drive risk mitigation 

• Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna 

• Provide clear, accurate, consistent, and timely communications 

• Advance good infrastructure and security practices and culture 

• Partner Collaboration work with Cloud Engineering, Systems Engineering, and AI Engineering, as well as Network Engineering, Identity and Access Management, Builder Tools & Platforms, IT, Cybersecurity, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner 

• Manage multiple initiatives: 

• Cloud modernization  

• Rationalize infrastructure platforms, tooling, and service models that underpin AI workloads.  

• Identify and eliminate redundant, unsupported, or non‑scalable infrastructure patterns that impede AI adoption. 

• Enable standardized, secure, and supportable “AI‑ready” infrastructure foundations that accelerate time‑to‑value while managing cost and risk. 

• Ensure infrastructure rationalization aligns with AI governance, data protection, and compliance requirements. 

• Define and track KPIs related to platform consolidation, cost optimization, risk reduction, and AI enablement readiness. 

• Lead and drive infrastructure service management improvements and process optimization initiatives, including infrastructure patch and vulnerability management. 

• Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain antiracist policies and processes

Here’s What You’ll Need (Minimum Qualifications)

• 8+ years of program management experience, preferably in infrastructure engineering 

• Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills 

• Technical background in infrastructure engineering, with a strong understanding of ITSM 

• Experience in running programs within a cross-functional, global team of mixed engineering, architecture, and operations. 

• Ability to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion 

• Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback 

• Proven ability to operate in highly matrixed environments and influence without direct authority. 

Here’s What You’ll Bring to the Table (Preferred Qualifications)

• Strong understanding of cloud platforms (AWS, Azure) 

• Familiarity with infrastructure concepts: compute, storage, networking, containers, Kubernetes 

• Working knowledge of AI/ML infrastructure needs (GPUs, distributed training, data pipelines, MLOps) 

• Influential, inclusive, and trusted partner compassionate to the