Senior Scientist, Flow Cytometry

Senior Scientist, Flow Cytometry

Summary of the Group 

The Flow Cytometry group is part of Dynamic Omics/ Centre for Genomics Research (CGR) and Discovery Sciences within AstraZeneca, and work across all therapeutic areas: Oncology, Cardiovascular, Renal and Metabolism (CVRM), Respiratory and Immunology (R&I), Vaccines and Immunotherapies (V&I), and Rare Diseases. The team supports over 600 scientists globally and delivers key data to projects across all phases of the drug discovery and development, and we work with all modalities from small molecules to biologics. The Flow Cytometry Center of Excellence is among the leading flow cytometry organizations worldwide (as recently recognized by the International Society for Advancement of Cytometry), equipped with state-of-the-art instrumentation and cutting-edge technology and expertise. 

Introduction to role

In this role, you will support the operations of the team in Gaithersburg, MD, with a particular focus on flow cytometry core lab experience and cell sorting. You will also participate in collaborations with multiple therapeutic areas. The successful candidate will have the opportunity to work and grow in a fast-paced environment under the supervision of senior staff members.

Accountabilities

In this role, you will serve as a primary resource to:

• Support the daily operation and maintenance of flow cytometers with a specific focus on cell sorting, and ensure accurate acquisition and management of data under local and global flow cytometry leadership

• Collaborate on innovative immunology/flow cytometry projects and/or automation solutions to support Oncology and BioPharma within AstraZeneca

• Be an expert in multicolor flow cytometry, review and analyze data, interpret experimental results, and summarize data for presentations and reports with accountability for accuracy

• Contribute to the development of new technological platforms such as Imaging Flow Cytometry

• Demonstrate excellent collaborative and pro-active problem-solving skills to include identifying a problem and taking appropriate actions and knowing when to seek guidance

Essential Skills/Experience

• PhD degree (or equivalent experience) in Immunology, Bioinformatics, Engineering or a related quantitative discipline and 3+ years of relevant experience, or a Masters with 5+ years, or a Bachelor’s with 8 years of directly relevant outstanding performance

• Cell sorting and flow cytometry core experience

• Track record of scientific excellence in immunology, flow cytometry and/or automation

• High-content and/or spectral flow cytometry experience

• Experience with a variety of flow cytometry data analysis and bioinformatic tools, including FlowJo, FCS Express, OMIQ, or Cytobank

• Great teamwork and communication skills, both verbal and written

• Strong multi-tasking, time management and organizational skills

Desirable Skills/Experience

• Programming skills such as Python and R are desirable

• Experience in automation is desirable

• Experience in understanding and analyzing other omics data (e.g. transcriptomics, mass spec) is a plus

• Microscopy experience is desirable

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. 

At AstraZeneca, we are at the forefront of creating new solutions that put patients at the core. We harness digital, data, and analytics to reimagine healthcare's future and deliver improved outcomes beyond core medicine. Our collaborative culture drives innovation, empowering us to unleash creativity and bring modern approaches to everyday challenges. Join us as we push boundaries within regulatory limits, leveraging technology to redefine patient experiences across their entire journey.

Ready to make a difference? Apply now to join our team!

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