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GE

Principal Medical (Science) Director - Immunology (Rheumatology-Nephrology)

Genentech
South San Francisco, United Statesfull_timeVerifiedPosted 8 Jan 2026
💰 $241,900/yr

About the role

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. 

 

The Opportunity

We're seeking a dynamic, patient-focused medical leader to join the US Medical (USM) Immunology team. This critical "player/coach" people leadership role is responsible for the day-to-day oversight, in partnership with the Therapeutic Area Lead, of the Rheumatology and Immune-Mediated Kidney Diseases Medical Network and portfolio. Reporting to the Therapeutic Area Lead, you will manage a group of Medical Directors/Medical Science Directors, providing exceptional clinical, scientific, and people leadership.  

In USM, we focus on broadening opportunities for patient access by ensuring that health care stakeholders have the evidence they need on our products and the confidence in that evidence to make informed treatment decisions. As a key pillar in the broader Genentech organization, USM has a pivotal role in bridging internal partner functions (including Research, Product Development, Commercial, and Government Affairs) and collaborating across the dynamic healthcare ecosystem to ultimately deliver better patient outcomes while making care more accessible and affordable for all.

The Principal Medical Director / Medical Science Director drives and guides medical strategy and tactics aimed at maximizing medical progress, while serving as the guardian for high standards of compliance, ethics, and safety. They will play a critical role to establish and maintain professional relationships with key medical experts in their field and will oversee all aspects of medical product support including collaboration with the relevant stakeholders to drive timely data generation and dissemination. They are expected to maintain an in-depth understanding of the medical strategy and relevant clinical and payer issues, while ensuring Genentech's partners understand key trends and shifts in the external healthcare landscape. They understand and evaluate their team and organization’s opportunities and constraints and build capabilities with an enterprise mindset. 

Key Responsibilities

  • Lead with a dynamic, people-first approach that empowers teams, fosters collaboration, and cultivates an inclusive, high-performance culture

  • Attract and retain top talent to meet current and future needs

  • Co-own with the team, the medical value proposition of product / pipeline & its contextualization in given therapeutic area(s) in order to implement medical strategies and tactics

  • Consistently engage with customers (patients, payers, healthcare professionals, professional societies, & cooperative groups) to understand their evolving medical needs and identify knowledge gaps & opportunities for collaboration, & scientific exchange through various channels to drive medical progress 

  • Drive timely development and execution of high quality Phase IIIb/IV clinical trials and investigator-initiated research including study design, protocol writing, approval, implementation and conduct, clinical monitoring, data interpretation and study reports 

  • Maintain an in-depth understanding of relevant medical strategy in the context of the healthcare landscape & customers for the US & represent the US perspective in global conversations

  • Collaborate with key stakeholders to prioritize the most important work, meet enterprise resource needs, and ensure fluidity and flexibility of people across activities (initiatives, projects, WPTs, etc.)

  • Create a culture grounded in trust, mutual respect and transparency in decision making that empowers individuals to self-organize and prioritize

  • Serve as a trusted resource for the team, including providing mentorship to direct reports and support in decision making; empower individual contributors closest to the work to make decisions while providing input as requested 

  • Identify and address training and development needs, inspire high performance by providing strategic leadership, setting goals, removing roadblocks, providing feedback, and coaching to capabilities, and actively promote an inclusive environment by supporting coaching, mentoring, and development opportunities.

Who You Are

Qualifications & Experience

  • Advanced Clinical/Science degree (e.g., MD, PhD, PharmD) 

  • 7+ years of pharmaceutical / biotechnology industry experience

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Company

Genentech

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