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Research Associate, Process Development Upstream
Avid BioservicesUnited Statesfull_timeVerifiedPosted 10 Oct 2025
💰 $80,000/yr($65,800/yr – $80,000/yr)
About the role
Looking to join a passionate team dedicated to developing and manufacturing life-saving biopharmaceuticals? Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes. Your Role: The Research Associate in Process Development - Upstream will develop and optimize scalable cell culture processes and contribute to transferring the process to Avid Manufacturing. In addition, the Research Associate will maintain production equipment and will research and implement new methods and technologies to enhance process operations.
- Responsible for mammalian cell culture process development and optimization including but not limited to recombinant protein production, cell adaptation to suspension or serum-free conditions, media/feed screening comparing growth and productivity in various media, growing and maintaining cells in shake flasks, wave and stirred tank bioreactors. Responsibilities also include seed train development, production bioreactor inoculation, maintenance, sampling, and feeding, and cell culture harvest/clarification.
- Work with many different kinds of mammalian cell lines (CHO-GS, CHO-DG44, CHO-M, CHO-S, NSO, HEK, etc) utilizing aseptic techniques, and apply a good understanding of the effect of general metabolic pathways (nutrient usage, expression system, etc.) physical (morphology, pH, osmolality, etc.) as well as mechanical (agitation speeds, oxygen and pH control, etc.) parameters on cell growth and recombinant protein production.
- Preparation of various cell culture media and feed formulations from scratch.
- Operate, troubleshoot, and maintain cell culture equipment such as bioreactors and analyzers.
- Scale up and tech transfer cell culture and harvest processes to the Manufacturing department.
- Analyze growth, production, and nutrient usage data, create data spreadsheets and graphs in Excel or JMP, document data and findings for traceability and regulatory requirements, write technical and summary reports, generate slide decks, and lastly, communicate findings and participate in scientific discussions within the group and with clients.
- Work with minimal supervision on projects of routine or low to moderate complexity.
- Research and implement new methods and technologies to enhance operations.
- Perform other duties as assigned.
- B.S. degree in a Biological Science
- Minimum of 1-2 years of relevant industry experience with demonstrated working knowledge of scientific principles.
- You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.
- Your written and verbal skills are out of this world, and you communicate with clarity and confidence.
- You have exceptional multitasking skills and an unparalleled attention to detail that ensure the smooth running of everything.
- You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.
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