Scientist, Medicinal Chemistry

Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

What We Do:

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. (*in collaboration with AbbVie)

About the Role:

Responsible for the design, synthesis, purification, and characterization of intermediates and bioactive compounds through the use of techniques such as column chromatography (e.g., high performance liquid chromatography, automated normal phase purification), nuclear magnetic resonance and parallel or combinatorial synthesis. Prepares technical reports, summaries, protocols, and quantitative analyses. Responsible for the communication and presentation of results to the project team in order to facilitate effective decision making.

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Your Contributions (include, but are not limited to):

Your Contributions (include, but are not limited to):

• Plays key role in the rapid optimization of lead molecules utilizing modern technology available to medicinal chemists such as automated synthesis and purification

• Participates in a multidisciplinary team committed to the continuous improvement of the lead optimization process as well as the expeditious identification of development compounds

• Designs, plans and conducts synthesis of intermediates and analog libraries as well communicates results to the project or program team

• Other duties as assigned

Requirements:

Requirements:

• BS/BA degree AND 2+ years of relevant experience, including familiarity utilizing any or all of the following: parallel synthesis, lab automation, and purification in the optimization of lead compounds is preferred OR

• MS/MA degree in Synthetic Organic Chemistry preferred AND some similar experience noted above OR

• PhD in Synthetic Organic Chemistry or related field preferred AND some related postdoctoral experience preferred

• Working knowledge of any or all of the following: organic synthesis, parallel synthesis, medicinal chemistry, lab automation, and purification in the optimization of lead compounds is preferred

• Recognizes fundamental anomalies in data points and identifies issues in experiments / processes

• Begins to understand how to think outside of the technical process a