Staff Scientist, Synthesis

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labeling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.

 In 2019, Eurofins generated total revenues of EUR € 4.56 billion, and has been among the best performing stocks in Europe over the past 20 years.

Eurofins BioPharma Product Testing has delivered expert scientific support to companies working to improve human and animal health. As a member of the Eurofins BPT team, you will work alongside respected technical experts dedicated to scientific excellence in a process driven regulatory compliant environment.  

Job Description

Eurofins BPT-Columbia is looking for a Staff Scientist to join our Synthesis team located in Columbia, Missouri. The Staff Scientist is a professional level position involved in performing research in the laboratory as a synthetic and medicinal chemist applying the latest knowledge and techniques in the field.  Advance the assigned program and contribute to the synthesis and identification of a lead or development candidate.  Planning their own work and supervising day-to-day activities in the laboratory working under prescribed procedures (protocols, standard operating procedures, methods, etc.).

Duties include:

• Conducting multiple-step synthesis using carbon-14C and tritium radioactive isotopes.
• Preparation of stable isotope labeled compounds as internal standards in LCMS analysis.
• Completing complex work for research and development under CGMP and/or GLP guidelines for studies, documentation, etc.
• Planning conducting and monitoring studies to ensure data accuracy and report quality.
• Writes reports on studies.
• Providing complex analytical work on projects and studies using a range of analytical techniques and instruments.
• Working with independence on studies and assignments. 
• Typically serves as technical leader within a group or team and may serve as project leader/study director on assigned projects.

The ideal candidate would possess:

• Extensive training and experience in multi-step synthesis, and knowledge of NMR, UV, mass spectrometry and FTIR spectra analysis for interpretation of new identities.
• Firm understanding of modern Organic Chemistry concepts, reaction mechanism, and the ability to use them in the design of synthesis target molecules.
• Ability for conducting literature search for synthetic route development.
• Separation techniques required for purification of organic compounds including re-crystallization, chromatography and TLC analysis.
• Advanced knowledge in various analytical instrumentation, especially HPLC.
• Adherence to GMP (preferred).
• Superior knowledge of scientific discipline; basic relevant technical skills; ability to read and understand protocols, SOPs, and technical guidelines.
• Compliance with, and knowledge of, regulatory guidelines and company SOPs (CGMP, GLP) is required.
• Good organizational skills; ability to follow direction and good communication skills are required.
• Ability to consult with clients and knowledge of date submission requirements for clients is necessary.
• Superior skill in handling radioactive or toxic chemicals.
• Ability to apply mathematical operations to such tasks as frequency distribution, determination of test reliability and validity, analysis of variance, correlation techniques, sampling theory, and factor analysis.
• Ability to apply principles of scientific thinking to a complex range of intellectual and practical problems.
• Ability to deal with a variety of abstract and concrete variables where only limited standardization exists.

Qualifications

• Bachelor’s degree in relevant field such as chemistry, biochemistry, biology, chemical engineering, pharmaceutical sciences, or other directly related field or degree with comparable coursework in the above areas and a minimum of five years of experience in a directly relevant setting.
• Master’s degree in a relevant field and three years of directly relevant experienc