MSAT Senior Principal Scientist, Physician Communications

Job Description

The MSAT Senior Principal Scientist, Physician Communications, will serve as the critical interface between commercial Casgevy manufacturing operations, Manufacturing Science and Technology, internal Commercial teams, and external physician stakeholders. This role will be instrumental in ensuring clear, concise, and accurate communication, in alignment with Vertex-approved content,  regarding individual patient outcomes in manufacturing, addressing physician inquiries, and facilitating a collaborative approach to optimize the customer experience .
The ideal candidate will possess a strong scientific and/or clinical background, experience with GMP manufacturing, exceptional communication skills, and the ability to translate complex technical information into easily understandable insights for a diverse audience. This individual will be a key resource in supporting our commitment to patient well-being and product excellence.

Key Duties and Responsibilities

• Physician Communication: Serve as the primary point of contact for commercial teams in physician communications regarding manufacturing/patient outcomes, including potential deviations, delays, or other issues. Provide timely and transparent updates, answering questions and addressing concerns in a clear, empathetic, and scientifically sound manner.
• Internal Collaboration & Coordination: Work closely with manufacturing, quality control, quality assurance, and MSAT investigation teams to gather comprehensive information on patient-specific manufacturing runs. Synthesize complex data and technical findings into digestible summaries for physicians and commercial teams.  Work with Vertex Legal and Commercial to evolve the agreed/allowed communication content.
• Issue Resolution & Investigation Support: Partner with scientific teams to understand the root cause investigations of manufacturing anomalies that may impact manufacturing outcomes. Provide physicians with relevant insights into these investigations, without disclosing proprietary information.
• Cross-Functional Liaison: Facilitate effective communication between commercial teams, manufacturing, and scientific groups to ensure a unified understanding of patient cases and to support commercial strategies with accurate technical information.
• Documentation & Reporting: Maintain detailed records of physician interactions, inquiries, and manufacturing outcome discussions. Contribute to internal reports summarizing trends in patient outcomes and physician feedback.
• Training & Education: Potentially assist in developing educational materials or providing training to commercial teams on manufacturing processes and common queries related to patient outcomes.

Required Education Level

• Advanced degree (Ph.D., MD, PharmD, M.S.) in a relevant scientific or medical discipline (e.g., Cell Biology, Immunology, Biomedical Engineering, Chemical Engineering, Biochemistry).

Required Experience

• Minimum of 5-7 years of experience in the biopharmaceutical industry, preferably with direct experience in cell and gene therapy, manufacturing, and/or clinical development.
• Demonstrated experience in a role requiring significant scientific or medical communication with external stakeholders, particularly healthcare professionals.
• understanding of GxP regulations and manufacturing processes within the biopharmaceutical and ATMP industry.
• Exceptional written and verbal communication skills, with the ability to explain complex scientific and technical concepts clearly, simply and concisely to non-experts.
• Proven ability to work collaboratively in a cross-functional team environment.
• Excellent problem-solving skills and the ability to remain calm and professional under pressure.
• Strong analytical skills and attention to detail.
• Ability to travel occasionally, <10%

Pay Range:

$164,900 - $247,400

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer