Associate Scientist, Cell Therapy

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

South San Francisco, California, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
 

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
 

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for an Associate Scientist, Cell Therapy to be in South San Francisco, CA.
 

Purpose:
Are you an independent and highly motivated scientist with experience in cell therapy? If so, then we are actively recruiting a talented individual to support us in these areas. We are a critical part of Therapeutics Discovery, responsible for the identification and characterization of novel CAR T cell therapies. Within the Cell and Genomic Medicine Group, our group utilizes high-throughput screening methods and analysis to characterize and develop cutting edge cell therapies. This position will contribute towards the development of a novel platform to generate and characterize CAR T cells for multiple tumor indications!
 

You will be responsible for:

• Executing cell therapy projects with supervision from senior team members 

• Conduct hands-on laboratory work to evaluate CAR T cell libraries and clonal constructs in primary cells using a variety of in vitro assays such as transducing primary cells and evaluating T cell phenotype of selected constructs 

• Perform downstream functional assays including cytotoxicity assays and cytokine secretion assays

• Execute pre-designed multicolor flow cytometry panels to interrogate cell typing and phenotypic response 

• Be responsible for lab management duties such as ordering reagents, performing preventative maintenance of key lab equipment, and ensuring compliance of safety standards

• Analyze data and present results to team members and group leaders 

• Communicate regularly, transparently, and accurately within the department and to other collaborators as a key point of contact

• Employ new workflow analytics and tools including automation to continually identify innovative chances for process improvement that would permit efficiency and acceleration

• Able to manage time and elevate relevant issues to team members and group leadership
   

Qualifications/Requirements:

• Minimum of a Bachelor’s or Master’s Degree within Biological Sciences or related field is required and a minimum of 1 year of hands-on cell culture experience

• Proficiency with culturing mammalian cells, both primary and immortalized

• Familiarity with cell therapy workflows: primary cell isolation, activation, transduction, and cryopreservation 

• Familiarity with immunostaining methods, flow cytometry, ELISA is a plus

• Experience using data analysis tools such as FlowJo and GraphPad Prism is a plus 

• Excellent communication, organization, and interpersonal skills

• Experience with team-based collaborations

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with dis