Senior Manufacturing Systems Engineer – MES Platform Lead

Career Category

Information Systems

Job Description

Join Amgen's Mission to Serve Patients

If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

Senior Manufacturing Systems Engineer – MES Platform Lead

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What you will do

Let’s do this. Let’s change the world. In this vital role as a Platform Lead you will drive the strategy, architecture, standards, and lifecycle for Amgen’s MES PASX ecosystem across a global network of manufacturing sites. You will collaborate closely with Site MES Teams,  Development Teams, Business Teams, Subject Matter Experts and other stakeholders to maintain high-quality, high-value, scalable MES solutions that meet Amgen’s business needs.

• Own the global strategy and roadmap for the MES PASX platform which is used across all manufacturing sites; ensuring platform scalability, reliability, security, data integrity and business alignment.

• Define and maintain technical standards for the platform architecture and configuration, planning out improvements and removal of aging technology, ensuring adherence to PASX and Amgen best practices.

• Partner with the global Business Owner to co-own the business roadmap and standards for the system, creating alignment across the network and propagating best practices. Expand business usage of the platform to meet Amgen’s business goals.

• Serve as the principal Amgen SME for capital and expansion projects. Scope out MES deliverables for projects, and guide system integrator teams to achieve successful deployment and startup of systems, compliant with Amgen standards.

• Lead a Global Program for managing the lifecycle of MES PASX across the network. Work with MES System Owners at the sites to plan out and implement major and minor version upgrades to address bug fixes, cyber remediation, lifecycle upgrades.

• Maintain global procedures, configurations and qualification strategies  for the MES Platform and work with site teams to ensure systems are maintained in accordance with Amgen and regulatory requirements.

• Work with business stakeholders in Manufacturing, Engineering, PD, and Data Science teams to help create and/or improve data products that utilize process and equipment data stored in MES, to fulfil business needs across the network. 

• Own the strategic vendor relationship to manage contracts, SLAs, and technical engagement with Körber and key service partners; negotiate licensing & support terms, influence product roadmaps, and oversee escalation resolution.

• Apply best practices to analyse business requirements, develop architectural designs, evaluate technology solutions, and ensure alignment with industry best practices and standards.

What we expect of you

Basic Qualifications:

• Doctorate degree OR

• Master’s degree and 4 to 6 years of Life Science/Biotechnology/Pharmacology/Information Systems experience OR

• Bachelor’s degree and 6 to 8 years of Life Science/Biotechnology/Pharmacology/Information Systems experience OR

• Diploma and 10 to 12 years of Life Science/Biotechnology/Pharmacology/Information Systems experience

Preferred Qualifications

• Proven experience in designing, deploying, and maintaining Körber’s PASX MES system.

• Hands‑on with PASX along with associated integrations to Level 2 and Level 4 systems.

• Pharma / GxP regulated‑environment experience.

• Strong background in industrial data‑integration protocols and platforms (MSI, OPC UA, Aveva Pi, Batch Management Systems, Kepware).

• Strong background in query languages and database technologies such as Oracle and PostgreSQL

• Customer‑centric mindset with a track record of building trusted stakeholder relationships.

• Self‑motivated and quick to learn new technologies; adept at cross‑functional collaboration.

Functional Skills

Must‑Have

• Deep understanding of manufacturing systems, data flows, and integrations.

• Strong grasp of OT/IT layering (ISA‑95/ISA‑99) and secure network design.

• Knowledge of load balancers, Windows Failover Clusters.

• Excellent problem‑solving skills for complex manufacturing challenges.