GSK is currently looking for a Senior Scientist to join our team in Upper Providence, PA.  This role is for a scientist responsible for delivering key non-clinical safety data both in traditional clinical pathology sciences as well as immune-safety for projects across the R&D portfolio. 

You will be an integral part of a high performing team that measures biomarkers for target-organ toxicity and adverse immune effects on nonclinical studies.  You will contribute to the interpretation of the clinical relevance of your data as it supports safe progression of clinical candidates in patients.   In this role you may perform the following job-related activities; together with other appropriate tasks, as requested by management:

Key Responsibilities and Accountabilities

• Focus of the job will cover both clinical pathology and immune-related biomarkers.

• Provide subject matter and technical expertise on relevant study endpoints.

• Perform testing/data analysis and interpretation related to clinical pathology laboratory analyses: hematology, clinical chemistry, coagulation, urinalysis, immunoassay-based biomarkers, blood smear, bone marrow smear and other relevant diagnostic capabilities to monitor animal health.

• Perform testing/data analysis and interpretation related to immune profiling: high dimensional flow cytometry, targeted transcriptomics, multiplex immunoassays and bioassays.

• Work cooperatively in a team that coordinates multiple simultaneous study activities.

• Responsible for timely communication of study data and interpretation to key stakeholders, generation of data tables/figures and writing reports.

• Support automation of laboratory workflows.

• Ensure scientific data integrity for accuracy and quality.

• Conduct work in accordance with study protocols, Standard Operating Procedures (SOPs), and GSK policies.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• BS in Clinical Laboratory Sciences/Medical Technology or Biology-related field (e.g., Biology, Biochemistry, Microbiology)

• 2 or more years relevant work experience in nonclinical/clinical laboratory and/or immunology laboratory

• Experience delivering data with traditional clinical pathology technologies (hematology and clinical chemistry analyzers) or specialized immune assays (flow cytometry, immunoassays, transcriptomics)

• Experience in maintaining accurate and detailed laboratory records in alignment with data integrity expectations and ensure compliance with all relevant protocols and safety guidelines.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Strong knowledge in multiple clinical pathology laboratory areas including hematology, clinical chemistry, and other relevant capabilities.

• Experience in profiling immune biomarkers with state-of-the-art multiplex technologies (e.g., high dimensional flow cytometry, targeted transcriptomics, multiplex immunoassays and bioassays). 

• Demonstrable experience in scientific critical thinking and independent planning, design and execution of experiments to test hypotheses.

• Proficiency in automated workflows to accelerate delivery.

• Experienced with compilation, analysis, visualization and interpretation of complex datasets.

• ASCP certification

• Experience with troubleshooting and resolving technical issues related to experimental processes or complex laboratory instrumentation.

• Demonstrable timely delivery of scientific data that meets acceptable data integrity standards.

• Experience in working closely with multidisciplinary teams and collaborating across organizational boundaries.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on