Senior Program Manager

Site: Massachusetts General Physicians Organization, Inc.

 

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

 

 

Job Summary

The Division of Neuropsychiatry and Interventional Psychiatry at Mass General Brigham and Harvard Medical School is a clinical neuroscience division that integrates research and innovation (basic, translational, and clinical), clinical care (TMS, ECT, Ketamine, and Neuropsychiatry clinical services), and training (clinical and research fellowships, residents, and graduate students).
Receiving supervision from the Division Chief, the Senior Program/Project Manager will lead research operations for a large and dynamic research group with multiple grants, projects, and staff.
This role requires a professional with strong expertise in human research/clinical trials operations and working knowledge of research finance, able to serve as the operational backbone of the Division Chief’s portfolio while building infrastructure and systems that can be adopted by other investigators in the division.
The Senior Program Manager will serve as the primary operational partner to the Division Chief, coordinating closely with junior research staff and principal investigators/faculty in individual division labs, as well as with the department- and hospital-level pre- and post-award teams for research administration, ensuring a balance between centralized oversight and distributed implementation.

 

Qualifications

1. Human Research Operations & Team Leadership

• Direct protocol development, regulatory compliance, study activation, and study execution across the Division Chief’s research portfolio.
• Lead Study Management System Oversight, ensuring effective use of platforms such as OnCore or REDCap:

  Protocol & Study Setup – Oversee the accurate documentation and activation of protocols and amendments.

  Participant Management – Oversight of enrollment, consent, and visit scheduling.

  Data Capture & Quality Control – Ensure timely and accurate data entry, integration with EHR/EDC systems.

  Regulatory & Compliance Monitoring – Track IRB approvals, safety reporting, and maintain GCP-compliant audit trails.

  Financial & Resource Tracking – Oversee study budgets, billing compliance, and resource allocation.

  Reporting & Analytics – Generate real-time dashboards and reports for investigators and leadership.

• Develop and enforce Standard Operating Procedures (SOPs) for research operations.
• Provide training and mentorship to research staff to ensure high-quality, compliant study execution.
• Oversee recruitment, onboarding, and professional development of research assistants and junior staff; serve as their administrative supervisor under a matrix reporting model.
• Foster a positive, inclusive, and compliant workplace culture aligned with MGB and departmental values.

2. Grant Administration & Program Finances

• Manage pre- and post-award activities for the Division Chief’s research portfolio, in close collaboration with hospital and departmental research management teams.
• Serve as point person for grant submissions to MGB, NIH, and other funders; refine the submission pipeline by building efficient processes and templates.
• Prepare, monitor, and update budgets, forecasts, and spending reports for multiple funded projects.
• Coordinate with central teams on contracting, cost transfers, salary allocations, and grant closeouts.
• Ensure financial compliance with NIH, federal, sponsor, and institutional guidelines.
• Provide leadership with financial dashboards and projections to guide decision-making and ensure appropriate use of project resources according to project goals, timelines, and milestones.
• Review costs and lead cost-reduction efforts to ensure financial sustainability and compliance.

3. Strategic Infrastructure Development

• Develop onboarding curricula and training workflows to standardize research staff preparation across the lab and division.
• Design and implement research management systems, workflows, and templates that improve operational efficiency, compliance, and reporting (e.g., protoc