Director, Molecular Science

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

The mission of the Innovation Lab is to increase the diagnostic yield of our exome and genome products and reduce the time to diagnosis for patients with an undiagnosed hereditary disease. The big goal is to deliver personalized and actionable health insights to every person who orders a genetic test from GeneDx. Achievement of our goals will require a culture of innovation, where creativity, experimentation, and the pursuit of new ideas are encouraged and embraced. Individuals are empowered to think critically, take risks, and challenge the status quo, to generate breakthrough solutions and drive positive change.

Summary:

We are seeking an accomplished and creative Director of Molecular Science to lead molecular research and innovation initiatives. This role is responsible for overseeing the design, execution, and strategic direction of molecular biology programs, including genomics, proteomics, gene editing, and biomarker discovery. The ideal candidate will bring deep scientific expertise, strong leadership, product development experience, and a passion for advancing molecular science and genomic testing. 

Job Responsibilities:

• Initiate, lead, and manage molecular science research programs designed to improve diagnostic testing for rare diseases.
• Oversee the design and execution of experiments involving DNA/RNA technologies, gene expression, CRISPR, sequencing, and molecular diagnostics.
• Ensure scientific rigor, data integrity, and compliance with regulatory and ethical standards.
• Collaborate with cross-functional teams, including laboratory innovation, bioinformatics, translational genetics, biostatistics, clinical research, regulatory affairs, and product development.
• Evaluate and integrate emerging molecular technologies and platforms, including DNA/RNA sequencing, proteomics, functional genomics and cytogenetics.
• Mentor and develop scientific staff, fostering a culture of innovation, collaboration, and continuous learning.
• Represent the organization in scientific forums and research collaborations.
• Manage budgets, timelines, and resource allocation for molecular science initiatives.

 People Manager:

• No

Education, Experience, and Skills:

• D. in Molecular Biology, Genetics, Biochemistry, or a related field.
• 10+ years of experience in molecular research, with at least 5 years in a leadership role.
• Proven track record of scientific innovation, publications, and/or patents in molecular science.
• Expertise in molecular techniques such as PCR, qPCR, NGS, gene editing, and molecular diagnostics.
• Strong leadership, communication, and project management skills.
• Experience in regulated environments (e.g., GLP, CLIA, FDA) is a plus.

 Certificates, Licenses, Registrations: N/A

Physical Demands:

• Ability to stand, walk, and sit for extended periods.

Work Environment:

• Fully Remote

Acknowledgements

The above job description is not intended to be an all-inclusive list of duties and standards of the position.  Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor.   

#LI-REMOTE

Pay Transparency, Budgeted Range$183,664—$229,580 USD

~

Science - Minded, Patient - Focused. 

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most. 

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to