Scientist II/Senior Scientist I, Protein Analytical Characterization
AbbVieAbout the role
Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.
Job Description
Discovery Biotherapeutics and Genetic Medicine (BGM) at AbbVie is seeking a highly motivated and experienced scientist to join its Protein Sciences Analytical Team. This position offers a unique opportunity to contribute to various Discovery Research Therapeutic Areas (TAs) and Projects by providing in-depth analytical and functional characterization of biologics and biopharmaceutical products, such as complex protein antigens, monoclonal antibodies, multi-specifics, and other antibody-like biologics. The ideal candidate will have a strong background in protein analytical characterization, particularly mass spectrometry, to discern protein critical quality attributes (identity, post-translational modifications, physiochemical properties), prior demonstration of innovative problem solving and troubleshooting, and will foster productive collaborations with other functional groups and TAs. This is an excellent opportunity for a motivated scientist to make a significant impact in a collaborative and innovative environment. Join us in bringing innovative medicines to patients!
Key responsibilities:
- Independently develop and execute mass spectrometry workflows for comprehensive characterization of biologics and biotherapeutics (including intact, reduced, subunit, and peptide mapping).
- Develop, optimize, validate, and execute innovative analytical methods to characterize complex proteins/glycoproteins, antigens, and novel protein-based therapeutics.
- Ensure optimal functioning, calibration, and maintenance of laboratory equipment; proactively troubleshoot and resolve technical or experimental issues to minimize operational downtime.
- Resolve key project challenges and obstacl
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